Effects of Red Fruit Oil on Exercise Endurance and Oxidative Stress in Rats

Abstract

This study investigated the effect of red fruit oil on biomarkers of oxidative stress in maximal physical activity. Fourty rats were divided into 4 groups. The control group (I) was administered with 1.5 ml distilled water, intervention groups (II), (III) and (IV) were administered with different doses of Red Fruit Oil (0.15 ml/kgBW, 0.3 ml/kgBW, and 0.6 ml/kgBW, respectively). All groups were trained to swim for 4 weeks and then were forced to swim without a load until being exhausted. The malondialdehyde, glutathione peroxidase levels and time of swimming to exhaustion were measured in all groups. The results showed that MDA level obtained was decreasing significantly (P<0.05), glutathione peroxidase and time of swimming was increasing significantly (P< 0.05) in the intervention groups. The results suggest that red fruit oil can obviously reduce MDA level, increased glutathione peroxidase and endurance and delay fatigue induced by maximal physical activity in the rat.

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“…The production of cortisol in the body suppresses the production of brain-derived neurotrophic factor (BDNF), which protects against malondialdehyde (MDA) toxicity as a marker of oxidative stress caused by reactive oxygen species (ROS) [5]. Physical activity could trigger an increase in malondialdehyde (MDA) levels and decrease Superoxide Dismutase (SOD) levels in the body [6,7]. The body naturally has an antioxidant system that aims to prevent damage caused by ROS, including the enzymes Superoxide Dismutase (SOD), Glutathione Peroxidase (GPx), and Catalase [8].…”