Effects of Rosuvastain on Bone Healing

Abstract

Statin has been used in other indication for their principle discovery due to their pleotropic effects. In the present study we would like to test the hypothesis of healing effects of rosuvastatin on induced bone lesion model in a rabbits. To do so, a bone injury rabbit model were used and the rabbit was administered rosuvastatin daily and sacrificed continuously for histopathology at day 7, day 14, and day 21. Results indicated that rosuvastatin induced beneficial healing process on the bone injury. Conclusion: bone healing could be a target for healing using rosuvastatin.