Effects of seasonal allergic rhinitis on selected cognitive abilities

Marshall, Paul; O’Hara, Christine; Steinberg, Paul Ian

doi:10.1016/s1081-1206(10)62273-9

Cited by 120 publications

(104 citation statements)

References 18 publications

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“…It is associated with impairments in how patients function in day-to-day life (1053). It has been known for a long time that having an allergic reaction causes significant fatigue and mood changes (1054), some impairment of cognitive function (1055,1056), depression and anxiety (1057,1058). Impairments on QOL and work and school performance are common, particularly in patients with moderate/severe symptoms.…”

Section: Social Lifementioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,861

1,761

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Section: Social Lifementioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,861

1,761

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“…Also associated with the disease are fatigue and daytime sleepiness,[7,9] reduced work productivity,[10-12] impaired cognitive functioning,[13,14] reduced learning abilities,[15] and impaired sleep[16]. …”

mentioning

confidence: 99%

Nasal-Ocular Reflexes and Their Role in the Management of Allergic Rhinoconjunctivitis With Intranasal Steroids

Baroody¹,

Naclerio²

2011

World Allergy Organization Journal

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Allergic rhinitis is a common disorder and involves the reaction to environmental allergens with resultant nasal and eye symptoms. The pathophysiologic mechanisms of the eye symptoms in allergic conjunctivitis include a direct effect on the eye by deposited allergen and indirect effects related to the deposition of allergen in the nasal mucosa. One of these proposed mechanisms is the existence of a nasal-ocular reflex whereby the nasal allergic reaction leads to an afferent reflex response, the efferent limb of which results in eye symptoms. Among the treatments available for allergic rhinitis, intranasal steroids are most efficacious for nasal symptoms and have also shown sizeable efficacy related to eye symptoms. We speculated that the effect of intranasal steroids on eye symptoms in allergic rhinitis was related to their inhibition of the nasal-ocular reflex and present data previously generated from our laboratory to support this assumption in a nasal challenge model.

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“…13 Consequently, many of the sequelae of AR, such as fatigue, decreased cognitive functioning and work performance, and reduced QOL, may be caused or worsened by AR-related sleep impairment. [14][15][16][17] The importance of ARrelated sleep impairment is acknowledged in both the International Primary Care Respiratory Group (IPCRG) guidelines for the management of AR 18 and in the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines, 2 in which the presence of abnormal sleep is one of the factors that reclassifies the severity of AR from mild to moderate/severe. The achievement of unimpaired sleep, therefore, is a primary goal of AR treatment.…”

mentioning

confidence: 99%

Allergic rhinitis-induced nasal congestion: its impact on sleep quality

Storms¹

2008

Primary Care Respiratory Journal

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Allergic rhinitis (AR) is an extremely common health problem affecting 20 to 40 million Americans and between 10-25% of the world's population. Patients with AR suffer from both nasal symptoms (congestion, rhinorrhea, itching, and sneezing) and ocular symptoms (itching, redness, and tearing). The negative impact on sleep quality and quantity, and consequently on various aspects of the patient's life, is an under-recognised and under-treated component of AR morbidity. Nasal congestion, which is one of the most bothersome and prevalent symptoms of AR, is thought to be the leading symptom responsible for rhinitis-related sleep problems.In addition to reducing clinical symptoms, pharmacologic therapies for AR that specifically reduce inflammatory cells and mediators -and therefore nasal congestion and other symptoms -should also improve sleep quality and overall quality of life (QOL). Intranasal corticosteroids (INS) are the current mainstay of therapy for AR. Results of a number of clinical trials demonstrate that INS effectively reduce nasal congestion and ocular symptoms, improve sleep quality, and decrease daytime somnolence. Intranasal corticosteroids have also proved to be effective in reducing symptoms of acute rhinosinusitis and nasal polyposis, both of which also negatively impact on sleep quality. Intranasal corticosteroids are considered safe due to their low systemic bioavailability.

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Effects of seasonal allergic rhinitis on selected cognitive abilities

Cited by 120 publications

References 18 publications

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Nasal-Ocular Reflexes and Their Role in the Management of Allergic Rhinoconjunctivitis With Intranasal Steroids

Allergic rhinitis-induced nasal congestion: its impact on sleep quality

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