Effects of Seitz filtration on Plasma Trace Proteins Concerned with Blood Coagulation: A Quantitative Study

Fell, Colin; Johnson, Jared; Walter, Harry

doi:10.1093/ajcp/24.2.153

Cited by 14 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The bark contains alkaloids including ditaine, echitenine, echitamine (ditamine) and echitamidine together with triterpenes β-amyrin and lupeol. It has been reported as antimicrobial, antiamoebic, antidiarrhoeal, antiplasmodial, hepatoprotective, immunomodulatory, anti-cancer, antiasthmatic, free radical scavenging, antioxidant, analgesic, anti-inflammatory, anti-ulcer, anti-fertility, anaemia, chronic diarrhea, dysentery, menstrual disorders, malarial fever, colic and acute arthritis and wound healing activities (Dhar et al, 1977;Patil et al, 1999;Fell, 1954;Gandhi and Vinayak, 1990;Keawpradub et al, 1999). There are also reports available on the traditional use of this plant for its cardiotonic, anti-diabetic and anti-arthritic properties.…”

Section: Introductionmentioning

confidence: 99%

“…The bark, leaves and milky exudates of A. scholaris are used in India (Kirtikar and Basu, 1980;Nadkarni, 1976;The Wealth of India, Raw Materials, 2004;Pawan et al, 2011;Abhijit, 2011). Many isolated constituents from A. scholaris lack information on pharmacological activities (Patil et al, 1999;Fell, 1954;Gandhi and Vinayak, 1990;Keawpradub et al, 1999;Khan et al, 2003;Atta-urRahman et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Isolation and structure determination of nematicidal iridoid sweroside from Alstonia scholaris

Sultana¹

2013

J. Entomol. Nematol.

View full text Add to dashboard Cite

The methanol extract of aerial parts of Alstonia scholaris (sapthaparna) was found to possess good nematicidal activity against the plant parasitic nematode, Meloidogyne incognita. The active nematicidal compound was isolated from the methanol extract by column chromatographic techniques and purified by TLC. Chemical structure was determined by chemical and spectroscopic methods to be that of a sweroside. This is the first report of its isolation from A. scholaris. Among other pure compounds: 4, 6 and 7, it showed maximum mortality of 71, 89 and 91%, respectively, after 24 h, while after 48 h, compounds 4, 6 and 7 showed 88, 74 and 76% mortality, respectively. The plant is of economic importance having nematicidal value. These results showed that the compounds isolated from A. scholaris have potent nematicidal activity and may be responsible for the antinematicidal activity of whole plant.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Isolation and structure determination of nematicidal iridoid sweroside from Alstonia scholaris

Sultana¹

2013

J. Entomol. Nematol.

View full text Add to dashboard Cite

show abstract

“…the amount ofthe plasma passed through the pad are ofimportance in determining the ainouiit of prothrombiii adsorbed (Fell, Johnson and Seegers, 1954). In the latter connection, Tagcr and Lodge (1951a) did note that the CRF activity of the filtrate varied with the voluine of plasma passed through the pad.…”

Section: Efect Of Seitz Filtrationmentioning

confidence: 99%

Studies on the Mechanism of Action of Staphylocoagulase

Rubinstein

1958

Br J Haematol

View full text Add to dashboard Cite

“…Any prothroinbin or certain prothronlbin derivatives, when added to such deficient plasma, can compensate for the abnormal prothrombin molecule it contains. The assay procedure which employs Seitzfiltered plasma as a test medium for factor VII has also been studied in this laboratory (36) and contrary to some claims, such filtered plasma is no inore deficient in factor VII than normal plasma.…”

Section: Factor VII In Plasma or Serummentioning

confidence: 99%

Inactivation of Purified Autoprothrombin I With Antithrombin

Wh¹,

Schroeer²,

Kagami³

1964

Can. J. Biochem.

View full text Add to dashboard Cite

Autoprothrombin I, was obtained by activating prothrombin preparations with autoprothrombin C. Autoprothrombin I, was obtained by activating prothrombin with the use of calcium ions and purified platelet factor 3. Both of these prothrombin derivatives were found to be inactivated by plasma and serum. Autoprothrombin I, was studied most extensively and was found to be inactivated by purified antithrombin. When antithrombin was first combined to capacity with purified thrombin the power to neutralize autoprothrombin I was almost eliminated. Autoprothrombin I1 was not destroyed by antithrombin and was found in serum as the main procoagulant. Most likely it is not in plasma.Autoprothrombin I,, autoprothrombin I,, autoprothrombi11 C, and thrombin all have reactive groups that combine with antithrombin. The activity in 1 n~g of purified autoprothrombin I, was neutralized by 50 ml plasma. One milligram of autoprothrombin C was neutralized by 5 ml plasma, and 7 ml plasma was sufficient to neutralize 1 mg of thrombin. Antithrombin IV is regarded as a kinetic effect and not as a substance. From a review of the literature it is concluded that there is no adequate evidence for appreciable quantities of factor VII in serum, or that it occurs in plasma independent of prothrombin.

show abstract

Effects of Seitz filtration on Plasma Trace Proteins Concerned with Blood Coagulation: A Quantitative Study

Cited by 14 publications

References 0 publications

Isolation and structure determination of nematicidal iridoid sweroside from Alstonia scholaris

Isolation and structure determination of nematicidal iridoid sweroside from Alstonia scholaris

Studies on the Mechanism of Action of Staphylocoagulase

Inactivation of Purified Autoprothrombin I With Antithrombin

Contact Info

Product

Resources

About