“…Unlike osteocalcin, the change in CTX-1 after training was unclear. Studies by Alp 2 on premenopausal women and by Wen et al 49 on postmenopausal women showed that CTX-1 decreased after 2 months of training with moderate intensity in 60-85% of maximal heart rate, 40 min per session, five times per week and 75-85% of heart rate reserve, 90 min per session, three times per week, respectively. A study by Adami et al found that CTX-1 was unchanged after 1 month of training (90 min/session, 3-4 times/week).…”