Effects of smoking on quality of life following sinus surgery: 4‐year follow‐up

Abstract

Objectives The purpose of this study is to report on long-term outcomes in a prospective study comparing the quality of life outcomes in smokers and non-smokers undergoing functional endoscopic sinus surgery. Study Design Prospective clinical trial. Methods A total of 235 patients were prospectively enrolled at a single tertiary academic center. Preoperative SNOT-20 scores and comprehensive demographic and smoking data were obtained. Preoperative SNOT-20 scores were compared to postoperative SNOT-20 scores. Results Long-term followup results were available in 111/185 nonsmokers (60%) and 26/50 smokers (52%). Non-smokers had a mean preoperative SNOT-20 score of 26.2, a short-term followup score of 10.1 (mean 3.1 months) and a long-term followup score of 11.4 (mean 44.2 months). Smokers had a mean preoperative SNOT-20 score of 27.8, a short-term followup score of 5.7 (mean 3.1 months) and a long-term followup score of 8.3 (mean 40.3 months). The mean improvement in SNOT-20 scores for smokers was significantly greater than non-smokers in short-term followup (p=.044), however no significant difference in improvement was seen between smokers and non-smokers at long-term followup. Conclusions Both smokers and non-smokers continue to maintain a highly significant improvement in SNOT-20 scores following endoscopic sinus surgery at long-term followup. While smoking remains a well documented cause of medical morbidity, smokers maintained an improvement in quality of life after long-term followup from endoscopic sinus surgery in this prospective study.

Association between cigarette smoking and interleukin-17A expression in nasal tissues of patients with chronic rhinosinusitis and asthma

“…Patients were considered smokers if they reported regular or ongoing smoking in the 12 months prior to surgery. [25,26] Patients who reported never having smoked cigarettes on a regular basis were considered as nonsmokers.…”

The Effect of Smoking on Quality of Life following Sinus Surgery: 10-Year Follow-Up

“…While these current studies demonstrate that passive and active smoking contribute to CRS, long-term results on smoking after FESS have not been sufficiently evaluated [20]. Our previously published data show that smokers actually have similar if not improved quality of life scores compared to nonsmokers and that smoke-induced CRS may represent a different subset of disease [18,19,20]. The present study showed a trend towards an increased prevalence of nasal polyposis and revision surgery in the nonsmoking group, although these findings did not reach statistical significance (p = 0.107 and 0.45, respectively).…”

“…Our data previously published in ‘The effects of smoking on short-term quality of life outcomes in sinus surgery' [18] demonstrated that smokers actually achieved greater short-term benefits compared to nonsmokers. This was further investigated in our study ‘Effects of smoking on quality of life following sinus surgery: 4-year follow-up' [19], which also showed that both smokers and nonsmokers continued to maintain similar improvements in SNOT-20 scores. In this article, we aim to review the same group of patients 10 years after sinus surgery to further elucidate the long-term effects of smoking and sinusitis.…”

Sinonasal inflammation in COPD: a systematic review

“…Finally, DAS et al [56] examined the QoL in a prospective study of 235 (21.3% smokers) undergoing surgery (FESS). SNOT-20 scores were obtained before and after surgery.…”