Effects of Strength and Endurance Training on Brain-derived Neurotrophic Factor and Insulin-like Growth Factor 1 in Humans

Schiffer, Thorsten; Schulte, Stefanie; Hollmann, W; Bloch, W.; Strüder, Heiko K.

doi:10.1055/s-0028-1093322

Cited by 109 publications

(87 citation statements)

References 21 publications

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“…Exercise types can be broadly categorized into strength (resistance) training and aerobic training. In all previous studies on resistance training, regular training did not increase resting BDNF levels [8,15,18,25]. With regard to different periods of exercise for resistance training studies, Goekint et al [8] and Levinger et al [15] evaluated a 10-week resistance training duration, Schiffer et al [18] used a 12-week period, and Yarrow et al [25] used a 5-week duration.…”

Section: Discussionmentioning

confidence: 99%

The effect of regular Taekwondo exercise on Brain-derived neurotrophic factor and Stroop test in undergraduate student

Kim

2015

J. Exerc. Nutr, Biochem.

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Young-Il Kim. The effect of Taekwondo Exercise on Brain-derived neurotrophic factor and Stroop test in undergraduate students. JENB., Vol. 19, No. 2, pp.73-79, 2015 [Purpose] The purpose of this study was to investigate the effect of Taekwondo exercise on Brain-derived neurotrophic factor and the Stroop test in undergraduate students.[Methods] Fourteen male subjects participated in this study. They were separated into a Control group (N = 7) and an Exercise group (N = 7). Subjects participated in Taekwondo exercise training for 8 weeks. They underwent to Taekwondo exercise training for 85 minutes per day, 5 times a week at RPE of 11~15. The taekwondo exercise training comprised an aerobic exercise (20min) mode and a dynamic exercise (65min) mode. All data were analyzed by repeated measures two-way ANOVA.[Results] There were no significant differences in the physical characteristics of the subjects. Although weight and BMI showed a tendency to decreased in the exercise group (EG). Also, neurotrophic factors (BDNF, NGF, IGF-1) were not significantly different after 8 weeks in the two groups. However, BDNF and IGF-1 showed a tendency to increase in the exercise group (EG). Finally, the Stroop test (word, color) results were significantly different(p < .05) in the exercise group (EG).[Conclusion] These finding suggest that 8 weeks of regular Taekwondo exercise training may increase cognitive functions (Stroop test). However the training did not statistically affect neurotrophic factors (BDNF, NGF, IGF-1) in undergraduate students.

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Section: Discussionmentioning

confidence: 99%

The effect of regular Taekwondo exercise on Brain-derived neurotrophic factor and Stroop test in undergraduate student

Kim

2015

J. Exerc. Nutr, Biochem.

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“…In a study by Goekint et al [15] , a period of strength training in sedentary subjects did not significantly change the concentration of growth factor compared to the control group. Another study reported that the resting concentration of BDNF was not infl uenced by strength training in young subjects [14] . Maximal speed and strength are known to be important determinants of sprint performance [22,23] .…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the differences in BDNF values between strength-and sprint-trained subjects may be partly due to the specifi c form of training. Heavy resistance exercise used in previous studies [14,15] was not combined with explosive types of weight training or speed concentrations in the international and the domestic sprinters were both higher than those in sedentary subjects (P < 0.05).…”

Section: Discussionmentioning

confidence: 99%

“…Although it is well-known that exercise increases BDNF transcription in the brain [8] , recent findings have reported that physical exercise, mostly aerobic endurance exercise, enhances circulating BDNF levels in healthy humans [9][10][11][12][13][14][15][16] . Interestingly, neither high-intensity strength exercise [17] nor general strength training [25] induces any significant changes in BDNF levels.…”

Section: Introductionmentioning

confidence: 99%

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Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

et al. 2011

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Objective Exercise is known to enhance circulating brain-derived neurotrophic factor (BDNF) levels in healthy humans. BDNF changes have been measured in endurance but not in strength exercise. The present study aimed to investigate whether anaerobic activity such as sprinting differentially alters basal plasma BDNF concentration. Methods Brazilian sprinters (100 m) at either the international (Olympics and Outdoor World Championships) (n = 14) or the domestic level (n = 8), and sedentary subjects (n = 15), were recruited. Plasma BDNF concentrations were analyzed by enzyme-linked immunosorbent assay. Results The basal plasma BDNF concentrations were signifi cantly higher in the international and the domestic sprinters than in the sedentary subjects. In addition, sprinters at the international level had higher plasma BDNF concentrations than those at the domestic level. Conclusion Our fi ndings suggest that increased basal plasma BDNF level is related to enhanced exercise performance.

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“…Perbaikan pasien RLS pada kelompok intervensi dalam penelitian ini diperkuat dengan penjelasan bahwa aktivitas fisik berupa latihan kekuatan merupakan stimulus adaptasi fungsional dan metabolik pada neuromuskular. Latihan kekuatan memberikan hasil pada penguatan otot rangka dan peningatan kekuatan maksimal (Schiffer, Schulte, Hollmann, Bloch, & Strüder, 2009). Latihan kekuatan juga telah terbukti memengaruhi fungsi kontrol motor (Graef, Michaelsen, Dadalt, Rodrigues, & Pereira, 2014).…”

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Pengaruh Latihan Kekuatan terhadap Restless Legs Syndrome Pasien Hemodialisis

Widianti¹,

Hermayanti

Kurniawan

2017

JKP

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AbstrakRestless legs syndrome (RLS) adalah gangguan sensorimotor yang banyak terjadi pada pasien hemodialisis (HD). Terapi farmakologi merupakan pilihan utama penanganan RLS yang justru berisiko menimbulkan efek samping. Optimalisasi fisik pasien HD melalui latihan kekuatan dinilai berpotensi efektif memperbaiki restless legs syndrome. Belum terdapat penelitian yang mengklarifikasi pengaruh latihan kekuatan terhadap RLS. Penelitian ini bertujuan untuk mengidentifikasi pengaruh latihan kekuatan terhadap skala RLS pada pasien HD di Unit Hemodialisis di RS Margono Soekardjo dan RSUD Banyumas. Metode quasi eksperimen dengan pre-post test with control group design ini menggunakan sampel sebanyak 32 pasien HD (15 pasien intervensi dan 17 pasien kontrol) dengan teknik cluster random sampling. Cluster random sampling dalam penelitian ini adalah penggunaan tempat penelitian sebagai kelas, yaitu satu rumah sakit untuk intervensi dan rumah sakit lainnya digunakan untuk kontrol. Latihan kekuatan pada ekstremitas atas dan bawah diberikan 2 minggu sekali saat proses hemodialisis berlangsung selama 8 minggu. Skala RLS diukur menggunakan IRLS Scale. Data yang terkumpul dianalisis menggunakan uji t tidak berpasangan. Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan antar kelompok dari usia, ureum, adekuasi, lama HD, jenis kelamin, penyakit kormobid maupun penggunaan obat. Antar kelompok memperlihatkan terdapat perbedaan nilai TIBC (p=0,000). Skala RLS kelompok intervensi menunjukan perbaikan dengan selisih mean -1 yang menandakan penuruan skala, adapun pada kelompok kontrol justru terlihat peningkatan kondisi RLS dengan selisih mean 1,29. Analisis antar kelompok terlihat signifikansi berbeda (p=0,035) yang menunjukkan terdapat pengaruh latihan kekuatan terhadap skala RLS. Latihan kekuatan penting sebagai bagian dalam pengelolaan pasien uremik RLS.Kata kunci: Latihan kekuatan, restless legs syndrome, skala RLS. Effect of Strength Training on Restless Legs Syndrome: Hemodialysis patients AbstracRestless legs syndrome (RLS) is a sensorimotor disorder that occurs mostly in hemodialysis (HD) patients. Pharmacological therapy is the main choice of RLS treatment that is at risk of side effects. Physical optimization of HD patients through strength training was considered as potentially effective to fix restless legs syndrome. No research has yet clarified the effect of strength training on RLS. Therefore, this study aims to identify the effect of strength training on RLS scale on HD patients in Hemodialysis Unit at Margono Soekardjo Hospital and Banyumas Hospital. The quasi experimental method with pretest and posttest with control group design was applied to 32 samples of HD patients (15 intervention patients and 17 control patients) by applying cluster random sampling technique. Cluster random sampling in this study is the use of research place as a class, for instance, one hospital for intervention group and the other one used for control group. Strength training on the upper and lower extremities is given every 2 weeks w...

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Effects of Strength and Endurance Training on Brain-derived Neurotrophic Factor and Insulin-like Growth Factor 1 in Humans

Cited by 109 publications

References 21 publications

The effect of regular Taekwondo exercise on Brain-derived neurotrophic factor and Stroop test in undergraduate student

The effect of regular Taekwondo exercise on Brain-derived neurotrophic factor and Stroop test in undergraduate student

Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

Pengaruh Latihan Kekuatan terhadap Restless Legs Syndrome Pasien Hemodialisis

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