Effects of surfactant molecular structure on the stability of water in oil emulsion

Cao, Guangwen; Du, Tong; Bai, Yujie; Yang, Tingyuan; Zuo, Jize

doi:10.1016/j.petrol.2020.107695

Cited by 23 publications

(7 citation statements)

References 33 publications

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“…The chemical structure of surfactants, such as the number of branched chains of hydrophobic alkyl chains, should be considered during the formation of microemulsions. Cao et al 27 reported that the emulsifying performance was weakened with multiple branched chains in the surfactant hydrophobic groups. Likewise, there are three branched chains in the hydrophobic groups of EL 20.…”

Section: Resultsmentioning

confidence: 99%

Formation of sacha inchi oil microemulsion systems: effects of non‐ionic surfactants, short‐chain alcohols, straight‐chain esters and essential oils

Song

Wang

et al. 2021

J Sci Food Agric

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BACKGROUND: This study reports the formation of sacha inchi oil (SIO) microemulsions for food and cosmetic applications. Effects of non-ionic surfactants, short-chain alcohols, essential oil and straight-chain esters on the phase behavior and formulation of U-type microemulsion were investigated. Pseudo ternary phase diagrams were constructed to assess the influence of these factors using water titration method. Structural transitions were measured along several water dilution lines using conductivity and viscosity tools.RESULTS: Among four different surfactants, Tween 80 solubilized the maximum oil and induced the formation of a U-type microemulsion system. Oil solubilization was decreased in the presence of short-chain alcohols. In addition, the system containing straight-chain esters as the cosolvent showed a higher expansion effect in the U-type areas than that containing essential oils. Finally, upon water dilution of three systems with SIO/ethyl acetate of 1:1, 1:2 and 1:3, microstructural transition from W/O to bicontinuous occurred at 200 g kg −1 (w/w) water content, and then to O/W structure at 650 g kg −1 (w/w) water content.CONCLUSION: Straight-chain esters as cosolvent is a potential strategy to extend the dilutability of SIO microemulsions.

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Section: Resultsmentioning

confidence: 99%

Formation of sacha inchi oil microemulsion systems: effects of non‐ionic surfactants, short‐chain alcohols, straight‐chain esters and essential oils

Song

Wang

et al. 2021

J Sci Food Agric

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“…Since P407 has a longer hydrophobic alky chain length than Tween 80, they showed smaller PS as the emulsifying effect was positively correlated to the emulsifier’s alkyl carbon chain length. In other words, the longer the alkyl carbon chain, the better the emulsifying effect [ 43 ].…”

Section: Resultsmentioning

confidence: 99%

Travoprost Liquid Nanocrystals: An Innovative Armamentarium for Effective Glaucoma Therapy

et al. 2023

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To date, the ophthalmic application of liquid crystalline nanostructures (LCNs) has not been thoroughly reconnoitered, yet they have been extensively used. LCNs are primarily made up of glyceryl monooleate (GMO) or phytantriol as a lipid, a stabilizing agent, and a penetration enhancer (PE). For optimization, the D-optimal design was exploited. A characterization using TEM and XRPD was conducted. Optimized LCNs were loaded with the anti-glaucoma drug Travoprost (TRAVO). Ex vivo permeation across the cornea, in vivo pharmacokinetics, and pharmacodynamic studies were performed along with ocular tolerability examinations. Optimized LCNs are constituted of GMO, Tween® 80 as a stabilizer, and either oleic acid or Captex® 8000 as PE at 25 mg each. TRAVO-LNCs, F-1-L and F-3-L, showed particle sizes of 216.20 ± 6.12 and 129.40 ± 11.73 nm, with EE% of 85.30 ± 4.29 and 82.54 ± 7.65%, respectively, revealing the highest drug permeation parameters. The bioavailability of both attained 106.1% and 322.82%, respectively, relative to the market product TRAVATAN®. They exhibited respective intraocular pressure reductions lasting for 48 and 72 h, compared to 36 h for TRAVATAN®. All LCNs exhibited no evidence of ocular injury in comparison to the control eye. The findings revealed the competence of TRAVO-tailored LCNs in glaucoma treatment and suggested the potential application of a novel platform in ocular delivery.

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“…Many studies have established [23][24] that surfactants with the number of carbon atoms in the chain of the molecule nс = 10-22 have the best emulsifying ability.…”

Section: Methodsmentioning

confidence: 99%

Anionic Bitumen Emulsions for Waterproofing

Antonova

Ayupov

2021

E3S Web Conf.

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Bitumen emulsions (BE) are widely used in road construction, for building and structure waterproofing. Storage stability is one of the main BE requirements. They should only break on contact with the surface. The sodium oleate effect as a surfactant on the stability of anionic bitumen emulsions for waterproofing purposes has been studied. Bitumen emulsions with increased storage stability have been developed. The optimal content of sodium oleate, providing a high complex of emulsion and resulting binder properties has been determined.

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Effects of surfactant molecular structure on the stability of water in oil emulsion

Cited by 23 publications

References 33 publications

Formation of sacha inchi oil microemulsion systems: effects of non‐ionic surfactants, short‐chain alcohols, straight‐chain esters and essential oils

Formation of sacha inchi oil microemulsion systems: effects of non‐ionic surfactants, short‐chain alcohols, straight‐chain esters and essential oils

Travoprost Liquid Nanocrystals: An Innovative Armamentarium for Effective Glaucoma Therapy

Anionic Bitumen Emulsions for Waterproofing

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