Effects of temperature on membrane potentials of lobster giant axon

Dalton, John C.; Hendrix, D. E.

doi:10.1152/ajplegacy.1962.202.3.491

Cited by 36 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If the temperature was increased above 25°C, the resting potential did not increase very much, and began to decrease at temperatures higher than 300 C. Irreversible damage seemed to occur to the fibre at temperatures above 360 C. In agreement with previous plots of resting potential versus temperature for several preparations including the present one (e.g. Dalton & Hendrix, 1962;Spyropoulos, 1966;Hinke & McLaughlin, 1967), Fig. 3 shows a case where the dependence is not linear, being steeper in the lower temperature range.…”

Section: Resultssupporting

confidence: 92%

See 1 more Smart Citation

Ionic permeability changes as the basis of the thermal dependence of the resting potential in barnacle muscle fibres

Fischbarg¹

1972

The Journal of Physiology

View full text Add to dashboard Cite

SUNMMARY1. The thermal dependence of the resting potential of isolated barnacle muscle fibres was larger (1-2 mV/0 C) than predicted by Nernst's equation (about 0*2 mV/0 C). A comparative study was made of the influence on thermal dependence of parameters related to (a) passive permeability and to (b) Na extrusion. 6. Although a small effect by a Na electrogenic pump cannot be excluded, the largest part of the thermal effect on the resting potential is concluded to depend on temperature-induced variations in relative ionic permeabilities to cations and anions. A model is proposed which can account for the data assuming that (a) each permeant ion associates to a separate site in the membrane, and (b) the ion-site equilibrium is temperature-dependent.

show abstract

Section: Resultssupporting

confidence: 92%

“…JORGE FISCHBARG Dalton & Hendrix, 1962;Spyropoulos, 1966;Hinke & McLaughlin, 1967), Fig. 3 shows a case where the dependence is not linear, being steeper in the lower temperature range.…”

mentioning

confidence: 96%

Ionic permeability changes as the basis of the thermal dependence of the resting potential in barnacle muscle fibres

Fischbarg¹

1972

The Journal of Physiology

View full text Add to dashboard Cite

show abstract

“…Photodynamic processes do not seem to be highly temperature dependent (Spikes & Livingston, 1969), and increases in temperature raise the resting potential and decrease spike duration (Dalton & Hendrix, 1962). Both of these effects are in the opposite direction to the results obtained here.…”

Section: Are Photodynamic Effects Reversible ?contrasting

confidence: 72%

Photodynamic alteration of lobster giant axons in calcium-free and calcium-rich media

Pooler

Oxford

1973

J. Membrain Biol.

View full text Add to dashboard Cite

Summary. Photodynamic alteration of Eosin Y-sensitized lobster giant axons was compared under conditions of calcium-rich and calcium-free media, to see whether the conflicting reported descriptions of the photodynamic effect can be resolved in terms of variations in calcium content of the bathing medium. Both a voltage clamp analysis (sucrose gap technique) and a microelectrode analysis (nonclamped axons) were used. In calcium-free media the characteristic photodynamic alterations of sodium channels (reduction in maximum conductance; increase in time to peak current) occurred at 40 % slower rates than in calcium-rich media, while the characteristic decrease in potassium current was unaffected by the calcium content. Photodynamic alteration depolarized nonvoltage clamped axons in both media, and there was an initial rapid depolarization phase in calcium-free media. All of these changes in both media were irreversible. In calcium-free media photodynamic alteration usually induced repetitive firing. The firing showed apparent reversibility, since it stopped after a period of time and could usually be reinitiated upon further illumination. It is proposed that decalcification does not alter the basic nature of the photodynamic effect, but complicates the axon response by its own independent effects. Dye-sensitized photodynamic alteration of excitable tissues has been observed as a phenomenon for over 50 years, as reviewed by Blum (1941). At the cellular level, considerable conflicts exist as to the essential nature of the photodynamic effect. On the one hand, Chalazonitis and co-workers (Chalazonitis, 1954;Chalazonitis & Chagneux, 1961) and Lyudkovskaya (1961) have described the process as excitatory and reversible. In studies on dye-treated Sepia giant axons illumination induced depolarization, oscillations in membrane potential, and repetitive firing, leading Chalazonitis and co-workers to view sensitized axons as model photoreceptor cells. On the other hand, voltage clamp studies carried out on lobster giant axons (Pooler, 1968(Pooler, , 1972 revealed irreversible decreases in sodium conductance and prolongation of the sodium conductance time course. No signs of lightinduced firing were observed in nonclamped axons. The conflicts could

show abstract

“…It is suggested that there is a tem perature-dependent fraction of the resting potential in lobster axons which is either not present or inactive in the squid axon, where the resting potential remains constant between 3 and 20°C. In the lobster axon within the same range, the resting potential increases from 72 to nearly 82 mv (40).…”

Section: Stampflimentioning

confidence: 92%

Conduction and Transmission in the Nervous System

Staempfli¹

1963

Annu. Rev. Physiol.

View full text Add to dashboard Cite

Effects of temperature on membrane potentials of lobster giant axon

Cited by 36 publications

References 0 publications

Ionic permeability changes as the basis of the thermal dependence of the resting potential in barnacle muscle fibres

Ionic permeability changes as the basis of the thermal dependence of the resting potential in barnacle muscle fibres

Photodynamic alteration of lobster giant axons in calcium-free and calcium-rich media

Conduction and Transmission in the Nervous System

Contact Info

Product

Resources

About