Effects of Testosterone Proprionate on Lymphoid Tissues and Antibody Production in Chickens

Breitenbach, Robert P.; Pauly, Lioba

doi:10.3382/ps.0400542

Cited by 4 publications

(1 citation statement)

References 15 publications

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“…Antibody production in chicks has been reported to be severely inhibited by androgen given to chick embryos by dipping fertilized eggs on the 4th to the 5th day of embryogenesis (Breitenbach & Pauly 1961; Glick & Sadler 1961). In contrast, treatment with estrogen at the same dose as testosterone on the 4th day of incubation has been clarified to induce elevated antibody production against foreign erythrocytes and bacteria in the hatched chicks (Kondo et al .…”

Section: Discussionmentioning

confidence: 99%

Effects of estrogen on estrogen receptor expression in the bursal cells of chick embryos and steroidogenic enzymes gene expression in the bursa: Relevance of estrogen receptor and estrogen synthesis in the bursa of chick embryos

Shin

Shiraishi

Narabara

et al. 2011

Animal Science Journal

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Estrogen has been reported to act on B cell genesis in the bursa of Fabricius of chick embryos. In this study, we attempted to demonstrate the hypothesis that B cell genesis is controlled by estrogen receptor (ER) in the bursal cells and steroidogenic enzymes synthesized in the bursa. We previously reported the presence of estrogen receptor α (ERα) in the bursa during the late stage of embryogenesis and an increase in the expression of ERα messenger RNA (mRNA) between the 13th day and 16th day. The number of ER-positive cells was maximal on the 16th day. In the present study, ER-positive cells in the bursa during the late stage of embryogenesis increased 4 h after β-estradiol treatment on the 14th to 18th day. The concentration of β-estradiol in the embryonic bursa increased. These results suggest that this stage of embryogenesis is critical in B cell development in the bursa in connection with the effect of estrogen treatment. Our findings also showed that the mRNA expression of five steroidogenic enzymes occurred in the bursa of chick embryos. These results suggest that estrogen is synthesized in the embryonic bursa and estrogen acts on the bursal cells in a paracrine fashion.

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Section: Discussionmentioning

confidence: 99%

Effects of estrogen on estrogen receptor expression in the bursal cells of chick embryos and steroidogenic enzymes gene expression in the bursa: Relevance of estrogen receptor and estrogen synthesis in the bursa of chick embryos

Shin

Shiraishi

Narabara

et al. 2011

Animal Science Journal

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Effects of testosterone on cellular composition of bursacytes. I. Profiles in size distribution and density-gradient separation.

1985

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Age-Dependent, and Testosterone and CyclophosphamideInduced Changes in Follicle-Associated Epithelium (FAE) of the Bursa of Fabricius in Chicks.

et al. 1996

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The influence of embryonic testosterone treatment on bursal epithelial pinocytotic activity. Developmental and Comparative Immunology, 6: 121-130. BREITENBACH, R.P. and L.K. PAULY, (1961) Effects of testosterone propionate on lymphoid tissues and antibody production in chickens. Poultry Science, 41: 542-547. GLICK, B. (1961) The influence of dipping eggs in male hormone solutions on lymphatic tissue and antibody response of chicken. Endocrinology, 69: 984-985. HASHIMOTO, Y. and M. SUCIMURA (1976) Histological and quantitative studies on the postnatal growth of the thymus and bursa of Fabricius of white pekin duck. Japanese Journal of Veterinary Research, 24: 65-76. HOUSSAINT, E. and MM. HALLET (1986) The follicleassociated epithelium in the bursa of Fabricius cell origin studied by means of quail-chick chimeras and monoclonal antibodies.

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Effects of Testosterone Proprionate on Lymphoid Tissues and Antibody Production in Chickens

Cited by 4 publications

References 15 publications

Effects of estrogen on estrogen receptor expression in the bursal cells of chick embryos and steroidogenic enzymes gene expression in the bursa: Relevance of estrogen receptor and estrogen synthesis in the bursa of chick embryos

Effects of estrogen on estrogen receptor expression in the bursal cells of chick embryos and steroidogenic enzymes gene expression in the bursa: Relevance of estrogen receptor and estrogen synthesis in the bursa of chick embryos

Effects of testosterone on cellular composition of bursacytes. I. Profiles in size distribution and density-gradient separation.

Age-Dependent, and Testosterone and CyclophosphamideInduced Changes in Follicle-Associated Epithelium (FAE) of the Bursa of Fabricius in Chicks.

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