Effects of the action of microwave-frequency electromagnetic radiation on the spike activity of neurons in the supraoptic nucleus of the hypothalamus in rats

Abstract

Acute experiments on white rats anesthetized with Nembutal (40 mg/kg, i.p.) were performed with extracellular recording and analysis of background spike activity from neurons in the supraoptic nucleus of the hypothalamus after exposure to electromagnetic radiation in the millimeter range. The distribution of neurons was determined in terms of the degree of regularity, the nature of the dynamics of neural streams, and the modalities of histograms of interspike intervals; the mean neuron spike frequency was calculated, along with the coefficient of variation of interspike intervals. These studies demonstrated changes in the background spike activity, predominantly affecting the internal structure of the spike streams recorded. The major changes were in the duration of interspike intervals and the degree of regularity of spike activity. Statistically significant changes in the mean spike frequencies of neuron populations in individual frequency ranges were also seen.

The Effects of Single and Repeated Exposure to 2.45 GHz Radiofrequency Fields on c-Fos Protein Expression in the Paraventricular Nucleus of Rat Hypothalamus

“…Several studies of brain activity have demonstrated that electromagnetic fields provoke responses in the central nervous system, alter bioelectric activity in the brain [50,51] modify the duration, intervals and regularity of the excitability of neurons in the supraoptic nucleus [52] or produce changes sometimes associated with observed from small increases in temperature (0.2-0.3°C), which are sufficient to activate thermoregulatory centres in the hypothalamus [53,54]. Radiofrequency that causes thermal stress has been observed to cause alterations in the concentrations of amino acids [55].…”

Impact of low intensity millimetre waves on cell functions

“…Neuronal activity is a particularly good marker for gauging stimulus thresholds since the neuronal membrane is optimised for sensing and in conducting electrical impulses with millisecond temporal response. Several research groups [8][9][10][11][12][13][14][15][16][17][18] have noted significant impact on neuronal activity induced in vivo by modest levels of millimetre-wave exposure (40-130 GHz, 1 -100 mW/cm 2 , seconds to minutes) that are not much higher than the MPE. Synchronisation of the firing rate of neurons in the hypothalamus of both rabbit and rat was observed at and below 10 mW/cm 2 [8,9].…”

Effect on Tumoral Cells of Low Intensity Electromagnetic Waves

“…According to literature, the millimeter-wave therapy increases the level of immune resistance, influences different stages of pathogenesis, changes enzymatic reaction activity and growth rate, destroys microorganisms, and increases the thermostability of DNA [4][5][6]. The literature has shown that millimeter waves have strong effect on the process and bioelectric activity of neurochemical functions of the brain, increase the cortical tension, and influence the spike activity of neurons in the supraoptic nucleus of the hypothalamus in rats [7,8]. Penetrating into the organism (the penetration depth of millimeter waves in tissues is about 1-1.5 mm due to high absorption by water molecules).…”