Mammalian cerebral cortex is accepted as being critical for voluntary motor control, but what functions depend on cortex is still unclear. Here we used rapid, reversible optogenetic inhibition to test the role of cortex during a head-fixed task in which mice reach, grab, and eat a food pellet. Sudden cortical inhibition blocked initiation or froze execution of this skilled prehension behavior, but left untrained forelimb movements unaffected. Unexpectedly, kinematically normal prehension occurred immediately after cortical inhibition, even during rest periods lacking cue and pellet. This ‘rebound’ prehension was only evoked in trained and food-deprived animals, suggesting that a motivation-gated motor engram sufficient to evoke prehension is activated at inhibition’s end. These results demonstrate the necessity and sufficiency of cortical activity for enacting a learned skill.DOI: http://dx.doi.org/10.7554/eLife.10774.001

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[1] Slab dip varies significantly, both between different, and along single subduction zones. Provided that old subducting plates are colder and denser than young plates, variations in the slab dip should correlate with slab age. However, recent statistical analyses do not show this expected correlation. We present the results of non-Newtonian numerical dynamic models where subduction is driven by means of a kinematic boundary condition. We systematically vary the age of both the overriding and subducting plates in order to test these effects on the slab dip at different depth ranges. We find that colder overriding plates result in shallower slab dips and episodes of flat slab subduction, as a result of the increased suction force in the mantle wedge. The influence of the thermal state of the overriding plate on slab dip is shown here to be more important than that of the age of subducting lithosphere. Modeling results are qualitatively compared to the large dip variability of the Cocos slab including a flat-slab segment. We suggest that this variability is likely related to the change of the thermal state of the overriding plates, with flat subduction occurring under cold lithosphere in southwestern Mexico and steep subduction under the warmer lithosphere of the northwestern Caribbean plate.