Effects of the Combined PDL/Nd:YAG Laser on Surgical Scars: Vascularity and Collagen Changes Evaluated byIn VivoConfocal Microscopy

Abstract

The aim of this study was to investigate the efficacy of the sequential combined 585 nm PDL and the 1064 nm neodymium:yttrium-aluminium-garnet laser (PDL/Nd:YAG) in the treatment of surgical scars and to evaluate the short-term effects by in vivo confocal microscopy (RCM) and the long-term effects by clinical assessment of the scars. Twenty-five patients were enrolled with 39 postoperative linear scars; each scar was divided into two fields. One half was treated with the combined PDL/Nd:YAG laser, whereas the other half remained untreated. Each scar was treated three times at monthly intervals. Scars were evaluated by an independent examiner, using the Vancouver Scar Scale. The combined PDL/Nd:YAG laser significantly improved the appearance of the scars. In order to study the short-term effects of combined laser treatment, six additional patients were enrolled with 7 postoperative linear scars. One half of scars was treated once with the combined PDL/Nd:YAG laser. One week after this laser treatment, both the treated and the nontreated parts of the scars were examined by dermoscopy and RCM. The dermoscopic pictures revealed improvements even in treated areas. In conclusion, the combined PDL/Nd:YAG laser was found to be effective in improving the quality and appearance of the surgical scars.

Picosecond laser for atrophic surgical scars treatment: in vivo monitoring of results by means of reflectance confocal microscopy

“…Concerns arise from cases of generalized pustular psoriasis flares, erythroderma or worsening psoriasis upon tapering or discontinuing systemic corticosteroids. 1,2 Despite the lack of relevant treatment guidelines, recent studies report that systemic corticosteroids are prescribed commonly for psoriasis. 3,4 Estimates from the U.S. National Ambulatory Medical Care Survey showed that 3.1% of psoriasis visits resulted in a systemic corticosteroid prescription, making it the second most frequently prescribed systemic medication for psoriasis prior to 2010.…”

“…1 Skin site involved is important since the location of scars in 'aesthetic' sites, such as the face, can cause psychological problems for patients. 2 In order to improve scar appearance, different therapeutic approaches have been employed. [2][3][4] However, the application of fractional picosecond-domain laser (PSL) 5,6 to atrophic scars has not been previously reported.…”

“…2 In order to improve scar appearance, different therapeutic approaches have been employed. [2][3][4] However, the application of fractional picosecond-domain laser (PSL) 5,6 to atrophic scars has not been previously reported. The aim of this study was to apply PSL system to atrophic scars and to report in vivo architecture of scars and variations occurring after treatment by means of reflectance confocal microscopy (RCM).…”

Picosecond laser treatment of atrophic and hypertrophic surgical scars: In vivo monitoring of results by means of 3D imaging and reflectance confocal microscopy

“…Depending on the location and on the size, they can be regarded as permanent stigmas. Therefore, scars can cause considerable aesthetic and psychological problems for patients as well as functional issues …”

Enhancement of Contour Using Laser Scar Treatment in the One-Stage Nasal Ala Reconstruction with Nasolabial Fold Flap

“…Krisztina Vas et al, one half of each of the postoperative linear scars immediately after suture removal was treated three times at monthly intervals with the combined 585/1,064 nm laser and the cosmetic appearances of the treated and untreated scar halves were compared. 18 In this patient case, we combined the effects of the known CO2 laser with the effect of the Cynergy. It was also confirmed that early treatment with laser treatment could have a good effect on scar treatment.…”