The purpose of this study was to investigate the influence of gutta-percha solvents on the bond strength of fiberglass post to root canal dentin. Forty bovine incisors were decoronated, prepared, filled, and randomly distributed into four groups (n = 10) according to the gutta-percha solvent used: control, xylene, eucalyptol and orange oil. After root canal treatment, the posts were cemented into the prepared root canals using a resin-based cement. A micro pushout test was executed, and the patterns of failure were assessed with microscopy. The data were analyzed using two-way ANOVA followed by Tukey's test. The control group exhibited greater bond strength compared to the eucalyptol group in the cervical and middle thirds of the root (P < 0.05); however, it did not differ significantly from the xylene and orange oil groups (P > 0.05). No difference was observed in the values of the xylene, orange oil, and eucalyptol groups (P > 0.05). The cervical third had higher values than the apical third for all tested solvents (P < 0.05). Adhesive failure between resin cement and dentin was the most frequent type of failure. The use of xylene and orange oil as gutta-percha solvents did not influence the bond strength of fiberglass posts to root canal dentin. (J Oral Sci 56, 105-112, 2014)