Effects of two doses of methylphenidate on simulator driving performance in adults with attention deficit hyperactivity disorder

Effects of smoking abstinence on adult smokers with and without attention deficit hyperactivity disorder: results of a preliminary study

“…Significant Group (ADHD, non-ADHD) × Condition (Satiated, Abstinent) interactions were observed for number of commission errors, RT standard error, response style (beta), and detectability (d'). *p<0.05, **p <0.01 Riccio et al 2001;Barkley et al 2005;Boonstra et al 2005;Gimpel et al 2005;Hood et al 2005;Schweitzer et al 2004;Turner et al 2005). Additional support for the role of dopamine in response inhibition comes from evidence that genes associated with dopamine functioning (e.g., DRD4 and DAT) are associated with differences in inhibitory control, even in healthy, non-ADHD individuals (Congdon et al 2007).…”

Treatment of adults with attention-deficit/hyperactivity disorder

“…Stimulant medications are also associated with fewer errors on a driving simulator in teens and adults with ADHD. Barkley and colleagues demonstrated that methylphenidate may have a benefi cial effect on some aspects of driving, for example less steering variability, slower driving speed, greater use of turn signals, and a fewer impulsive responses (Barkley et al 2005).…”

Attention Deficit Hyperactivity Disorder, Other Mental Health Problems, Substance Use, and Driving: Examination of a Population-Based, Representative Canadian Sample

“…However, other research has shown poor concordance between laboratoryor clinic-based measures of response to ADHD medication and actual performance (Thompson et al 2007). A simulator study found differences in only 3 of 18 measures between the ADHD placebo condition and the low or high doses of methylphenidate conditions (Barkley et al 2005). …”