Effects of ultrasound-guided brachial plexus block combined with laryngeal mask sevoflurane general anesthesia on inflammation and stress response in children undergoing upper limb fracture surgery

Gao, Yi; Dai, Pengqi; Shi, Lei; Chen, Wenjing; Bao, Wenjuan; He, Lanlan; Tan, Yongpan

doi:10.23736/s2724-5276.21.06740-9

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…In contrast, general anesthesia is more convenient for anesthesia management of patients, but it will affect the stability of hemodynamics of patients. Therefore, it is often combined with nerve block in clinic to improve postoperative outcomes in fracture surgery [ 19 , 25 , 26 ]. In our retrospective study, we analyzed the impacts of general anesthesia and nerve block combined with general anesthesia in patients undergoing lower extremity fracture.…”

Section: Discussionmentioning

confidence: 99%

[Retracted] Impacts of Ultrasound‐Guided Nerve Block Combined with General Anesthesia with Laryngeal Mask on the Patients with Lower Extremity Fractures

Yang

Bao

Gong

et al. 2022

Journal of Environmental and Public Health

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Objective. Surgical reduction is the leading approach to patients with lower extremity fractures. The options of anesthetic drugs during surgery are of great significance to postoperative recovery of patients. There is no consensus on the optimum anesthesia method for patients undergoing lower extremity fracture surgery. Our study is aimed at investigating the impacts of nerve block combined with general anesthesia on perioperative outcomes of the patients. Methods. In this retrospective study, 48 patients experienced general anesthesia only, and 42 patients received never block combined with general anesthesia. The perioperative hemodynamics was recorded, including mean arterial pressure (MAP), oxygen saturation of blood (SpO2), and heart rate (HR). Visual analogue scale (VAS) and Montreal Cognitive Assessment (MoCA) were carried out to evaluate postoperative pain and cognitive status. Furthermore, adverse reactions and recovery condition were observed between the patients receiving different anesthesia methods. Results. At 15 minutes and 30 minutes after anesthesia, as well as 5 minutes after surgery, significant lower MAP was observed in the patients treated with general anesthesia ( 83.04 ± 8.661 , 79.17 ± 9.427 , 86.58 ± 8.913 ) compared to those receiving never block combined with general anesthesia ( 90.43 ± 4.618 , 88.74 ± 6.224 , 92.21 ± 4.015 ) ( P < 0.05 ), and compared with general anesthesia group ( 68.5 ± 7.05 , 69.63 ± 7.956 , 72.75 ± 8.446 ), the combined anesthesia group ( 73.52 ± 9.451 , 74.17 ± 10.13 , 77.62 ± 9.768 ) showed obvious higher HR ( P < 0.05 ). No significant difference in SpO2 was found between the two groups at multiple time points ( P > 0.05 ). As for the score of VAS and MoCA, remarkably lower VAS and higher MoCA at 6 h, 12 h and 24 h after surgery were presented in the combined anesthesia group compared to general anesthesia group ( P < 0.05 ). At 24 h after surgery, the two groups showed normal cognitive function ( 26.33 ± 0.7244 vs. 28.55 ± 0.7392 ). Incidence of nausea and vomiting in the combined anesthesia group was lower than that of the general anesthesia group ( P < 0.05 ). The time to out-of-bed activity and hospital stay were shorter in the combined anesthesia group compared with general anesthesia ( P < 0.05 ). Conclusion. The application of never block combined with general anesthesia contributed to the stability of hemodynamics, alleviation of postoperative pain and cognitive impairment, along with decrease in adverse reactions and hospital stay in the patients with lower extremity fractures.

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Section: Discussionmentioning

confidence: 99%

[Retracted] Impacts of Ultrasound‐Guided Nerve Block Combined with General Anesthesia with Laryngeal Mask on the Patients with Lower Extremity Fractures

Yang

Bao

Gong

et al. 2022

Journal of Environmental and Public Health

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“…Ropivacaine is not only a potassium channel blocker, but also can inhibit the sodium ion conduction of nerve cells and has an obvious blockade and separation effect of sensory and motor nerves, which is conducive to inhibiting neuronal excitation and preventing the transmission of pain signals (Vadagandla et al, 2020). Using ultrasound-guided injection of ropivacaine into BPB can dynamically monitor the distribution and diffusion degree of anesthetic drugs, ensure accurate injection, effectively block sympathetic nerve, improve the success rate of nerve block, reduce the stress on the body and improve hemodynamics (Gao et al, 2022). We believe that after receiving sevoflurane with laryngeal mask and BPB with ropivacaine, children with humeral fracture can reduce the irritation of respiratory tract, prevent respiratory depression and cough, so SpO2 is in a relatively stable state, and MAP and HR are also improved.…”

Section: Discussionmentioning

confidence: 99%

Application Value of Sevoflurane Combined with Brachial Plexus Block in Children with Humeral Fracture Surgery and its Effect on Hemodynamics: A Clinical and Anatomical Study

Gui,

Xu,

Shu

et al. 2023

Int. J. Morphol.

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To observe the effect of sevoflurane combined with brachial plexus block (BPB) in children with humeral fracture surgery and its effect on hemodynamics. 84 children who received surgical treatment of humeral fracture in our hospital from September 2019 to September 2022 were selected. According to different anesthesia methods, the children were divided into control group and study group. The control group only received laryngeal mask sevoflurane; the study group received laryngeal mask sevoflurane combined with BPB. The operation situation, hemodynamic indexes, stress level, pain and adverse reactions of children was observed. The postoperative awakening time in the study group was lower than control group, the postoperative pain onset time in the study group was higher than control group (P<0.05). Intraoperative and postoperative 2 h, mean arterial pressure and heart rate in the study group were lower than control group (P<0.05). Preoperative, intraoperative, and postoperative 2h, there was no significant difference in oxygen saturation between the two groups (P>0.05). Postoperative 2h, the levels of serum cortisol, b-endorpin, norepinephrine and epinephrine in the study group were lower than control group (P<0.05). Postoperative 2 h, 12 h, 24 h, the visual analogue scale scores in the study group were lower than control group (P<0.05). There was no statistical difference in adverse reactions between the two groups (P>0.05). Sevoflurane combined with BPB is helpful to shorten the postoperative awakening time of children with humeral fracture, reduce the degree of postoperative pain, improve hemodynamics, and reduce stress response, and has good safety.

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Effects of ultrasound-guided brachial plexus block combined with laryngeal mask sevoflurane general anesthesia on inflammation and stress response in children undergoing upper limb fracture surgery

Cited by 2 publications

References 5 publications

[Retracted] Impacts of Ultrasound‐Guided Nerve Block Combined with General Anesthesia with Laryngeal Mask on the Patients with Lower Extremity Fractures

[Retracted] Impacts of Ultrasound‐Guided Nerve Block Combined with General Anesthesia with Laryngeal Mask on the Patients with Lower Extremity Fractures

Application Value of Sevoflurane Combined with Brachial Plexus Block in Children with Humeral Fracture Surgery and its Effect on Hemodynamics: A Clinical and Anatomical Study

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