Effects of variable viscosity on pulsatile flow of blood in a tapered stenotic flexible artery

Mukhopadhyay, Subrata; Mandal, Mani Shankar; Mukhopadhyay, Swati

doi:10.1002/mma.5355

Cited by 10 publications

(4 citation statements)

References 27 publications

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“…In this portray, a mathematical review of blood flow along with the stenotic and aneurysmal vessel has been analyzed to investigate the influence of narrowing of the blood vessel, expansion of the blood vessel and the intensity of aneurysm for the Newtonian case. A lot of Numerical techniques used to solve such problems are examined [ [41] , [42] , [43] ]. The detailed scientific inspection is carried out.…”

Section: Introductionmentioning

confidence: 99%

Effects of stenosis and aneurysm on blood flow in stenotic-aneurysmal artery

Hussain

Dar

Eldin

2023

Heliyon

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Section: Introductionmentioning

confidence: 99%

Effects of stenosis and aneurysm on blood flow in stenotic-aneurysmal artery

Hussain

Dar

Eldin

2023

Heliyon

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“…Several simulation studies focus on the impact of stenosis, or narrowing of vessels, on the flow of blood. In this context, the distribution of wall shear stresses and hydraulic resistance 39 , have been measured, with channel taper angle 37 , 39 , fluid velocity 38 , 39 , and viscosity 40 , each determining flow through tapered systems. In rigid particle suspensions, clogging can be delayed in a tapered microchannel by increasing the width at the outlet, thereby creating higher shear stresses that prevent suspended particles from adhering to the constriction wall to initiate clogs 28 .…”

Section: Introductionmentioning

confidence: 99%

Flow dynamics through discontinuous clogs of rigid particles in tapered microchannels

Majekodunmi

Hashmi

2022

Sci Rep

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Suspended particles flowing through complex porous spaces exhibit clogging mechanisms determined by factors including their size, deformability, and the geometry of the confinement. This study describes the clogging of rigid particles in a microfluidic device made up of parallel microchannels that taper from the inlet to the outlet, where the constriction width is approximately equal to the particle size. This converging geometry summarizes the dynamics of clogging in flow channels with constrictions that narrow over multiple length scales. Our novel approach allows the investigation of suspension flow dynamics in confined systems where clogs are formed both by sieving and bridging mechanisms simultaneously. Here, flow tests are conducted at constant driving pressures for different particle volume fractions, and a power-law decay which appears to be peculiar to the channels’ tapered geometry is observed in all cases. Compared to non-tapered channels, the power-law behavior shows flowrate decay is significantly weaker in tapered channels. This weaker flowrate decay is explained by the formation of discontinuous clogs within each channel. Micrographs of the clogged channels reveal clogs do not grow continuously from their initial positions around the channels’ outlet. Rather, new clogs spanning the width of the channel at their points of inception are successively formed as the cake grows toward the inlet area in each microchannel. The results show changes in particle volume fraction at constant driving pressure affect the clogging rate without impacting the underlying dynamics. Unexpectedly, analyses of the particles packing behavior in the microchannels, and post-clogging permeability of the microfluidic devices, reveal the presence of two distinct regimes of driving pressure, though only a small portion of the total device volume and channels surface area are occupied by clogs, regardless of the particle volume fraction. This novel investigation of discontinuous clogging over multiple particle diameters provides unique insights into additional mechanisms to control flow losses in filtration and other confined systems.

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“…During the past few decades, several studies on fluid dynamics through constricted arteries have been carried out to evaluate the flow pattern and the wall shear stress under steady and pulsatile flow conditions (Tu et al 1992, Misra and Chakravarty 1986, Mukhopadhyay et al 2011, Mandal et al 2014, Mukhopadhyay et al 2018aand Mukhopadhyay et al 2019. Most of these numerical studies considered blood as a Newtonian fluid.…”

Section: Introductionmentioning

confidence: 99%

Numerical Simulation of Mass Transfer in Pulsatile Flow of Blood Characterized by Carreau Model under Stenotic Condition

Mukhopadhyay

2021

JAFM

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The present numerical study deals with a mathematical model representing mass transfer in blood flow under stenotic condition. Streaming blood is considered as a non-Newtonian fluid characterized by Carreau fluid model and the vessel wall is taken to be flexible. The nonlinear pulsatile flow phenomenon is governed by the Navier-Stokes equations together with the continuity equation while that of mass transfer is governed by the convection-diffusion equation coupled with the velocity field. A finite difference scheme is developed to solve these equations accompanied bysuitable initial and boundary conditions. Results obtained are examined for numerical stability up to wanted degree of correctness. Various significant hemodynamic parameters are examined for additional qualitative insight of the flow-field and concentration-field over the entire arterial segment with the help of the obtained numerical results. Comparisons are made with the available results in open literature and good agreement has been achieved between these two results. Comparisons have been made to understand the effects of viscosity models for Newtonian and non-Newtonian fluids and also for rigid and flexible arteries.

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Effects of variable viscosity on pulsatile flow of blood in a tapered stenotic flexible artery

Cited by 10 publications

References 27 publications

Effects of stenosis and aneurysm on blood flow in stenotic-aneurysmal artery

Effects of stenosis and aneurysm on blood flow in stenotic-aneurysmal artery

Flow dynamics through discontinuous clogs of rigid particles in tapered microchannels

Numerical Simulation of Mass Transfer in Pulsatile Flow of Blood Characterized by Carreau Model under Stenotic Condition

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