Effects of Withania somnifera on the growth and virulence properties of Streptococcus mutans and Streptococcus sobrinus at sub-MIC levels

Evolution of Antimicrobial Activity of Leaf Extract of Withania somnifera Against Antibiotic Resistanct Staphylococcus aureus

“…Jain and Varshney reported the antibacterial activity of the methanolic extracts of the whole W. somnifera plant against E. coli, P. aeruginosa, S. aureus, S. mutans and C. albicans with zones of inhibition of 38, 36, 15, 38 and 32 mm, respectively [8]. As the results of Pandit et al methanol extract of W. somnifera demonstrated a broad antibacterial rang against Streptococcus mutans and Streptococcus sobrinus (MIC 0.125 -2 mg/mL) [22]. According to the study of Alam et al methanol extract of the plant displayed the highest activity against S. typhi (32.00 ± 0.75 mm zone of inhibition), whereas the lowest activity was against K. pneumoniae (19.00 ± 1.48 mm zone of inhibition) [23].…”

Inhibition of microbial adhesion to plastic surface and human buccal epithelial cells by Rhodomyrtus tomentosa leaf extract

“…8 Medicinal plants have been studied by many workers as an alternative treatment for a number of infectious diseases, especially in oral diseases. [9][10][11][12] A wide variety of plants and their active constituents have been reported for many biological activities which included anti-adherent properties, [13][14][15][16][17][18] exclusively an inhibition on adherence ability and biofilm formation of oral pathogens. 15,[19][20][21] Downy rose myrtle, Rhodomyrtus tomentosa (Aiton) Hassk, is an evergreen shrub native to Southeast Asia 22,23 and currently has no economic value.…”

Potentiation of NMDA Receptors byWithania somniferaon Hippocampal CA1 Pyramidal Neurons

“…Consumption of WS increases the capability of an individual to resist adverse environmental factors and creates a sense of mental well being (Weiner and Weiner, 1994). In addition, WS has a range of biological effects including cardio-protective (Dhuley, 2000;Gupta et al, 2004;Mohanty et al, 2004), anti-inflammatory (Bhattacharya et al, 1997) and anti-bacterial properties (Owais et al, 2005;Pandit et al, 2012), as well as promotion of thyroid hormone release (Panda and Kar, 1998). WS has been used without side effects for all age groups and sexes, and even during pregnancy (Sharma et al, 1985).…”