Effects of zinc bearing palygorskite supplementation on the growth performance, hepatic mineral content, and antioxidant status of broilers at early age

Abstract

ObjectiveThis study was conducted to investigate effects of zinc (Zn) bearing palygorskite (ZnPal) supplementation on growth performance, hepatic mineral content, and antioxidant status of broilers at early age.MethodsA total of 240 1-day-old Arbor Acres broiler chicks were allocated into 5 treatments with 6 replicates of 8 chicks each. Birds in 5 treatments were fed a basal diet supplemented with 0 (Control group; Analyzed Zn content: 81 mg/kg), 20, 40, 60, and 80 mg/kg Zn as ZnPal for 21 days, respectively. Blood, liver and intestinal mucosa were collected at 21 days of age.ResultsTreatments did not affect growth performance of broilers during the 21-day study (p> 0.05). The contents of hepatic Zn and magnesium (Mg) were linearly increased (p<0.001) by ZnPal supplementation. ZnPal inclusion linearly (p = 0.007) reduced malondialdehyde (MDA) concentration in serum. The activity of total superoxide dismutase (T-SOD) in liver increased linearly (p = 0.001) with concentration of ZnPal in diet. ZnPal inclusion linearly (p = 0.036) and quadratically (p = 0.005) increased T-SOD activity, and linearly (p = 0.012) increased copper/zinc superoxide dismutase (Cu/Zn SOD) activity in jejunal mucosa. The maximum responses of hepatic and jejunal antioxidant enzymes activities (T-SOD and Cu/Zn SOD) were found when supplementing the basal diet with 60 mg/kg Zn as ZnPal. Furthermore, ZnPal supplementation quadratically (p = 0.001) increased Cu/Zn SOD activity in ileal mucosa, and its maximum activity was observed in the diet supplemented with 20 mg/kg Zn as ZnPal.ConclusionZnPal supplementation did not alter growth performance of broilers. Dietary ZnPal inclusion could increase concentrations of hepatic trace minerals (Zn and Mg) and inhibit lipid peroxidation by reducing serum MDA accumulation, with the optimal dosage of Zn from ZnPal being 80 mg/kg diet (analyzed Zn content in the diet: 165 mg/kg), and 60 mg/kg Zn as ZnPal (analyzed Zn content in the diet: 148 mg/kg) was the optimum dosage for broilers to achieve maximum antioxidant enzyme activities.

Effect of zinc on the immune response and production performance of broilers: a meta-analysis

“…The other production performances of broiler, i.e., average daily intake, mortality, and carcass percentage, were not significantly affected by increasing zinc dose or the different forms of zinc (Tables 4, 5). This study in line with several studies which reported that zinc addition on broiler diet had no effect on average daily intake, mortality and carcass percentage [91][92][93]. In contrast, several studies reported that zinc addition on broiler diet affected average daily intake, mortality and carcass percentage [51,[94][95][96].…”

Zinc Supplementation Forms Influenced Zinc Absorption and Accumulation in Piglets

“…Previous studies showed that T-SOD, AKP, and 5′-NT activities were significantly affected by Zn deposition and can be used for the evaluation of body Zn status [ 28 ]. Several studies have shown that T-SOD, AKP, and 5′-NT levels were affected by different Zn supplementation forms [ 29 , 30 ]. Our current study showed that Zn-Met added in feed and ZnSO 4 dissolved in drinking water could increase the activities of AKP in the jejunum and T-SOD in the ileum as compared to the ZnSO 4 added in feed.…”

Potential adverse effects on animal health and performance caused by the addition of mineral adsorbents to feeds to reduce mycotoxin exposure

“…Moreover, Erwin et al (1998) demonstrated through an in vitro study that sodium bentonite has a strong affinity for pure carotene and can as well bind non-carotenoid pigments in feed (Erwin et al 1998). With regard to trace elements, adverse effects observed in farm animals have been attributed to the imbalance between dietary concentration of trace elements in feed and the amount of trace elements in the mineral adsorbents (Thilsing et al 2007;Grosicki and Rachubik 2010;Yang et al 2017).…”