Effects of Zingiber Officinale on Reproductive Functions in the Male Rat

Abstract

To investigate the effects of Zingiber Officinale on male reproductive functions and study the mechanisms underlying these effects, aqueous extract of Zingiber Officinale were administered orally to two groups of male rats at 500mg/kg b.w. and 1000mg/kg b.w. A third group served as control and received the treatment vehicle, distilled water. Treatment lasted for 14 and 28 days before sacrifice. Organ weight, epididymal sperm counts, motility, viability and morphology, seminal fructose, testicular malonhydialdehyde, and serum testosterone were determined. The treatment caused a significant increase (P<0.05) in the weight of the testis and epididymis. There were dose and duration dependent increases in sperm count and motility (P<0.05). There was also a significant increase (P<0.05) in serum testosterone level. Malonhydialdehyde levels were significantly reduced (P<0.05). Our results indicated that extract of Zingiber Officinale possesses pro-fertility properties in male rats which might be a product of both its potent antioxidant properties and androgenic activities.

Treatment Effects Of Onion (Allium cepa) And Ginger (Zingiber officinale) On Sexual Behavior Of Rat After Inducing An Antiepileptic Drug (lamotrigine)

“…An inclusive study showed that the effect of ginger on male procreation is as follows: in the mentioned study after treatment with ginger, the weight of testis and epididymis increased significantly, also the number of sperms was counted and their movements increased also. After treatment, testosterone increased and malonhydriodehyde was reduced (44). In another study, 25 Wistar rats were used, in order to study the influence of onion and ginger on spermatogenesis, and they was divided into 5 groups (four groups for study and one for control).…”

Aqueous Extract of Carica Papaya Linn Roots Halts Sodium Arsenite-Induced Renal Inflammation through Inhibiting Adenosine Deaminase, 8-Hydroxy-2′-Deoxyguanosine, C-Reactive Protein and Inducible Nitric Oxide Synthase Activity

“…After incubating at 37 o C for 60 minutes, nitrite levels, which correspond to an estimative of levels of NO, was determined spectrophotometrically at 540 nm, based on the reduction of nitrate to nitrite by VCl 3 using method described previously (23). Kidney nitrite and nitrate levels were expressed as nanomoles of NO per milligram of protein.…”

Reversible Antifertility Effect of Cassia tora Linn in Male Rats

“…Normal testicular function is dependent on FSH and testosterone is absolutely required for normal spermatogenesis [75][76][77][78][79][80] . FSH establishes a quantitatively normal Sertoli cell population, whereas androgen initiates and maintains sperm production, thus both hormones co-operate via independent functions to enable maximal spermatogenic output [81][82][83][84][85] .…”