Treatment Effects Of Onion (Allium cepa) And Ginger (Zingiber officinale) On Sexual Behavior Of Rat After Inducing An Antiepileptic Drug (lamotrigine)

Khaki, Arash; Farnam, Alireza; Badie, Arash Davatgar; Nikniaz, Hussein

doi:10.5152/balkanmedj.2012.045

Cited by 35 publications

(38 citation statements)

References 36 publications

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“…Sertoli cells control the entry and exit of nutrients, hormones and other chemicals into the tubules of the testis, as well as make the adluminal compartment an immune-privileged site. In our study, significant increase was observed in sertoli cells apoptosis and this is caused by the decrease in the cell population in testis and decrease in serum testosterone (Khaki et al, 2012a). The present study points to the possibility that electromagnetic fields (EMF) also lower serum testosterone levels (Khaki et al, 2013) and through induction of apoptosis in sertoli cells cause damage to blood testes barrier.…”

Section: Results Of Sertoli Cells Apoptosis Levelssupporting

confidence: 49%

“…Dietary polyphenols have received tremendous attention among nutritionists, food scientists and consumers due to their roles in human health. Research in recent years strongly supports a role for polyphenols in the prevention of degenerative diseases, particularly cancers, cardiovascular diseases and neurodegenerative diseases (Khaki et al, 2012a) label this ref since there are more than one Khaki et al 2012). Rosmarinic acid belongs to the group of polyphenols which are strong antioxidants that complement and add to the functions of antioxidant vitamins and enzymes as a defense against oxidative stress caused by excess reactive oxygen species (ROS).…”

Section: Results Of Sertoli Cells Apoptosis Levelsmentioning

confidence: 99%

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Effect of Rosmarinic acid on sertoli cells apoptosis and serum antioxidant levels in rats after exposure to electromagnetic fields

Hajhosseini¹,

Khaki²,

Merat³

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

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Section: Results Of Sertoli Cells Apoptosis Levelssupporting

confidence: 49%

Section: Results Of Sertoli Cells Apoptosis Levelsmentioning

confidence: 99%

Effect of Rosmarinic acid on sertoli cells apoptosis and serum antioxidant levels in rats after exposure to electromagnetic fields

Hajhosseini¹,

Khaki²,

Merat³

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

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“…Khaki et al (2012) studied the effects of onion (Allium cepa) and ginger (Zingiber officinale) on the sexual behavior of rats after treatment with an antiepileptic drug (lamotrigine). They observed that Vitamins C, E, and B were useful in reducing the toxic effects of free radicals on genital gonads (Khaki et al).…”

Section: Kamani M; Mhabadi J A; Atlasi M A; Seyedi F; Kamanmentioning

confidence: 99%

Protective Effect of Alcoholic Extract of Garden Cress Seeds on the Histopathological Changes of the Ventral Prostate in Streptozotocin Diabetic Rats

et al. 2017

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KAMANI, M.; MHABADI, J. A.; ATLASI, M. A.; SEYEDI, F.; KAMANI, E. & NIKZAD, H.Protective effect of alcoholic extract of garden cress seeds on the histopathological changes of the ventral prostate in streptozotocin diabetic rats. Int. J. Morphol., 35(3):1178Morphol., 35(3): -1184Morphol., 35(3): , 2017. SUMMARY:Diabetes mellitus is a common serious metabolic illness occurring worldwide that may lead to male infertility. Various plants have been used in the treatment of diabetes. In this study, the effect of garden cress (Lepidium sativum) seed extract on fasting blood sugar is assessed for its protective effect on histopathological changes in the ventral prostate gland of streptozotocine-induced diabetic rats. Fifty adult male Wistar rats were randomly selected into five groups. Group 1 was the control placebo group where rats received only 0.1 mL normal saline via gastric gavages. Rats in Group 2 received an intraperitoneal injection of STZ 60 mg/kg body weight and those with FBS >250 mg/dL were considered diabetic. In Group 3, diabetic rats received insulin (3 U/100 g body weight) while in Groups 4 and 5 diabetic rats received 0.1 ml of 200 and 400 mg/kg respectively of an ethanol extract of Lepidium sativum seeds by gavage daily. The prostate was removed and weighed before transfer to Bouin's solution for histological studies. Administration of the 200 and 400 mg/kg doses of Lepidium sativum seed extract increased epithelium height and decreased interstitial volume density and fibromuscular thickness of the prostate significantly. Also, the volume density of the epithelium, fibro muscular, lumen, and interstitial tissues were changed significantly. The results suggest that Lepidium sativum seed extract has beneficial effects as a protective agent against the detrimental effects of diabetes on the reproductive system of diabetic male rats.

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“…Khaki et al (2009Khaki et al ( , 2012 and Alagawany et al (2015) observed that numerous health benefits have been identified which attract researchers to investigate the validity of medical properties of these plants. They further stated that anti-oxidative properties of aqueous onion juice have been proved in studies conducted on animals, in which fresh onion juice had a positive effect on the sperm health and spermatogenesis in rats and rabbits (Khaki et al, 2012;Alagawany et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Semen quality characteristics of Koekoek breeder cocks influenced by supplemental inclusion levels of onion and garlic mixture at 35-41 weeks of age

Okoro

Mbajiorgu

2016

R. Bras. Zootec.

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-An experiment was conducted to determine the effect of varying dietary supplemental inclusion levels of onion and garlic mixture on semen quality characteristics of Koekoek breeder cocks aged 35-41 weeks. The experimental diets were isocaloric and isonitrogenous but with different supplemental inclusion levels of onion and garlic. A complete randomized design was used for the experiment. The three dietary supplemental levels based on garlic and onion supplemental inclusion levels were Q 0 (0 g onion and 0 g garlic per 600 g DM feed), Q 1 (2.5 g onion and 2.5 g garlic per 600 g DM feed), and Q 2 (5 g onion and 5 g garlic per 600 g DM feed) with each treatment having three replicates. A quadratic type equation was used to determine the onion and garlic levels for optimum semen quality characteristics. Daily supplementation with 5 g onion and 5 g garlic per 600 g DM feed increased progressive motile cells (%), actual life sperm count (×10 6 /nl), and live sperm (%) by 221.20%, 301.51%, and 352.43%, while 2.5 g onion and 2.5 g garlic per 600 g DM feed reduced them by 28.67%, 12.69%, and 19.00%, respectively. However, daily supplementation with 2.5 g onion and 2.5 g garlic per 600 g DM feed increased sperm count (×10 6 /nl) by 12.82%, whereas daily supplementation with 5 g onion and 5 g garlic per 600 g DM feed reduced it by 10.26% in Koekoek breeder cocks. Dietary onion and garlic supplemental inclusion levels of 3. 009, 3.191, 4.621, 6.601, 6.719, 2.327, 2.385, and 2.247 g per 600 g DM feed supported optimum progressive motile cells (%), immotile sperm cells (%), actual dead sperm count (×10 6 /nl), actual live sperm count (×10 6 /nl), live sperm (%), acrosome morphology defects (%), acrosome detachment (%), and acrosome swelling (%), with probability values ranging from 0.003 to 0.783, whereas minimum progressive motile cells (%) increase was achieved at an optimum onion and garlic supplementation levels of 3.009 g per 600 g DM feed. These findings have a lot of implications on the use of supplemental onion and garlic inclusion levels to enhance reproductive efficiency in Koekoek breeder cocks.

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Treatment Effects Of Onion (Allium cepa) And Ginger (Zingiber officinale) On Sexual Behavior Of Rat After Inducing An Antiepileptic Drug (lamotrigine)

Cited by 35 publications

References 36 publications

Effect of Rosmarinic acid on sertoli cells apoptosis and serum antioxidant levels in rats after exposure to electromagnetic fields

Effect of Rosmarinic acid on sertoli cells apoptosis and serum antioxidant levels in rats after exposure to electromagnetic fields

Protective Effect of Alcoholic Extract of Garden Cress Seeds on the Histopathological Changes of the Ventral Prostate in Streptozotocin Diabetic Rats

Semen quality characteristics of Koekoek breeder cocks influenced by supplemental inclusion levels of onion and garlic mixture at 35-41 weeks of age

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