2023
DOI: 10.1097/ms9.0000000000000756
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Efficacy and safety of inhaled nitric oxide administered during cardiopulmonary bypass for pediatric cardiac surgery: a systematic review and meta-analysis

Abstract: Background and aims: Cardiopulmonary bypass (CPB) utilized for cardiac surgeries has been associated with significant mortality and adverse outcomes. The benefits of incorporating nitric oxide (NO) into the CPB circuit have been reported in terms of reduced inflammation, enhanced dynamic circulation, oxygenation, and end-organ function. This systematic review and meta-analysis aimed to evaluate the efficacy and safety of inhaled NO introduced to the CPB circuit among pediatric patients undergoing v… Show more

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Cited by 2 publications
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“…Nitric oxide has been used successfully used in pulmonary hypertension and respiratory failures in neonates 9 . Furthermore, inhaled nitric oxide have been found to be beneficial in pediatric cardiac surgery patients during cardiopulmonary bypass 10 . Thus, it has been suggested to be a potential therapy for acute bronchiolitis.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Nitric oxide has been used successfully used in pulmonary hypertension and respiratory failures in neonates 9 . Furthermore, inhaled nitric oxide have been found to be beneficial in pediatric cardiac surgery patients during cardiopulmonary bypass 10 . Thus, it has been suggested to be a potential therapy for acute bronchiolitis.…”
Section: Introductionmentioning
confidence: 99%
“…9 Furthermore, inhaled nitric oxide have been found to be beneficial in pediatric cardiac surgery patients during cardiopulmonary bypass. 10 Thus, it has been suggested to be a potential therapy for acute bronchiolitis.…”
Section: Introductionmentioning
confidence: 99%