Efficacy Assessment of Avian Pasteurella multocida and Mycoplasma gallisepticum Local Vaccines

Ibrahim, Fatma F.; El-Ghany, Wafaa A. Abd; Rawy, Eman M. El; Shaker, Mona M.; El-Jakee, J.

doi:10.17582/journal.jahp/2021/9.3.213.221

Cited by 3 publications

(3 citation statements)

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“…While protection % against P. multocida type "D" challenge was 80% in rabbit groups vaccinated with P. multocida vaccine and 90% for the combined one in comparison with 0% for control group. These findings were consistent with previous studies (Fatma Fathy 2018;El-Maghraby et al 2019;Ibrahim et al 2021) who found that P. multocida adjuvanted vaccines were more effective against challenge with virulent strains of P. multocida types A and D.…”

Section: Resultssupporting

confidence: 93%

“…Also, Ibrahim et al (2021) concluded that the inactivated P. multocida Montanide adjuvanted vaccine gave long duration antibody titer when assessed by IHA test. Youssef and Tawfik (2011), when used the IHA test, found that inactivated rabbit Pasteurella vaccine adjuvanted with Montanide ISA-50 produced protective antibody titers against P. multocida and gave high and long-lasting antibody levels.…”

Section: Resultsmentioning

confidence: 99%

“…Both RHDV and Pasteurella are the two major problems in industrial rabbitries and both of them are incriminated in a lethal hemorrhagic infection (simultaneous infection) in rabbitries (Ibrahim et al, 2021;O'Toole et al 2022). For both RHDV and Pasteurella, the vaccination is made in order to increase the specific humoral immune response of the animal and protects against the two diseases.…”

Section: Introductionmentioning

confidence: 99%

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Preparation of Locally Prepared Inactivated Combined Vaccine of Rabbit Haemorrhagic Disease Virus Types 1 & 2 and Pasteurella multocida

2023

Int J Vet Sci

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A combined inactivated montanide ISA-70 adjuvanted vaccine against two types of rabbit viral hemorrhagic disease (RVHD) and Pasteurella multocida (P. multocida) was prepared. Another 2 inactivated vaccines were prepared too, one bivalent RHDV1 and RHDV2 against RVHD while the other single monovalent against P. multocida. The prepared vaccines were compared from the aspect of immune response up on the vaccinated rabbits. The comparison was based on the estimation of the humoral immune response for both RHDV and P. multocida by hemagglutination inhibition test (HI) and indirect hemagglutination test (IHA). Four groups of susceptible rabbits were used; one for each vaccine and the 4th group was control. The immune response was followed up for 24 weeks. Higher and earlier immune response against both RHDV1and RHDV2 were induced by combined oil emulsified vaccines at 1st week post vaccination (WPV) than bivalent inactivated RHDV vaccine. Using HI, the antibody titer reached maximum levels of combined oil vaccine (211.75, 211.5) for RHDV1 and RHDV 2 at the 12th weeks after vaccination, respectively. The same results were for P. multocida vaccine as the higher and earlier immune response against P. multocida was obtained from the combined vaccine than Pasteurella vaccine only. For P. multocida A and D, at the 6th week after vaccination, antibody titers of combined oil vaccine using IHA reached (218.5,218.2) respectively. The challenge test in the combined vaccine group revealed that, RHDV1 gave protection with 90%, and 100% for RHDV2 in the combined vaccine. As well as challenge test for Pasteurella gave protection with 90%. The developed combined inactivated montanide oil vaccines against Rabbit hemorrhagic disease types 1, 2 and Pasteurellosis appeared to be safe and effective in improving the immune response (onset and longevity). Immune protection against RHDV1, RHDV2 and P. multocida can be achieved with one manipulation decreasing the stress on animals and efforts.

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Section: Resultssupporting

confidence: 93%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Preparation of Locally Prepared Inactivated Combined Vaccine of Rabbit Haemorrhagic Disease Virus Types 1 & 2 and Pasteurella multocida

2023

Int J Vet Sci

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The effect of an antioxidant on the hematological profile of birds

Kuzmina

Petrov

Семенов

et al. 2021

IOP Conf. Ser.: Earth Environ. Sci.

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The research is devoted to the study of the influence of the modern antioxidant of the flavonoid group ‘Dihydroquercetin’ as part of the feed combination on the hematological profile and biochemical parameters of the blood of broiler chickens of the KOBB-500 cross. The content of hemoglobin and erythrocytes in the blood of broilers receiving dihydroquercetin increased, which indicates an increase in the intensity of redox processes in the body. The number of leukocytes in all groups was normal, but in the experimental groups their decrease was noted, which indicates the therapeutic and immunostimulating effect of the drug. Evaluation of protein metabolism by the content of total protein and the fraction of albumin in the blood serum showed its positive dynamics within the normal physiological values, which characterizes an increase in the intensity of assimilation processes in the bird’s body. The metabolism of carbohydrates was assessed by the content of glucose in it, and a decrease in its level indicates its increased consumption as an energy component for metabolic processes associated with intensive growth of chickens. An increase in the activity of alkaline phosphatase by 1.3-1.8 times is associated with the active growth of chickens.

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Fowl Cholera in Chickens: Current Trends in Diagnosis and Phenotypic Drug Resistance in Gondar City, Ethiopia

Geda

2024

Veterinary Medicine International

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Ethiopia, with an estimated chicken population of 17 million, serves as a source of high‐quality animal protein, helping to reduce malnutrition, improve nutritional status, and provide food and food products. However, Ethiopia has not fully leveraged the value of chicken production due to various bacterial diseases, with fowl cholera (FC) being the most common. Therefore, the objective of this review is to highlight the current trends in the diagnosis of FC in chickens and asses its phenotypic drug resistance patterns in Gondar City. FC is an infectious disease caused by Pasteurella multocida (P. multocida), which poses significant health and financial losses to the poultry industry. Culturally, the bacterium P. multocida can be isolated using bacteriological and biochemical tests from chicken infected with FC. Molecular‐based techniques such as capsular and lipopolysaccharide genotyping, as well as nucleic acid amplification tests through PCR assays, are also among the best methods used to detect P. multocida. In conclusion, understanding the current trends in diagnosing FC and assessing its phenotyping drug resistance, which helps in choosing effective antibiotics in Gondar City, is essential. It is also important to assess the disease‐associated factors that enhance the occurrence of the disease, in addition to providing the disease preventive and control measures and vaccination programs based on the diagnosis of its causative agent.

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Efficacy Assessment of Avian Pasteurella multocida and Mycoplasma gallisepticum Local Vaccines

Cited by 3 publications

References 1 publication

Preparation of Locally Prepared Inactivated Combined Vaccine of Rabbit Haemorrhagic Disease Virus Types 1 & 2 and Pasteurella multocida

Preparation of Locally Prepared Inactivated Combined Vaccine of Rabbit Haemorrhagic Disease Virus Types 1 & 2 and Pasteurella multocida

The effect of an antioxidant on the hematological profile of birds

Fowl Cholera in Chickens: Current Trends in Diagnosis and Phenotypic Drug Resistance in Gondar City, Ethiopia

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