Efficacy of a novel strategy for poststernotomy deep sternal infection after thoracic aorta replacement using a prosthetic graft

A combination of hydrodebridement with pulsed lavage and negative pressure wound therapies may enhance outcomes

“…NPWT with continuous or intermittent irrigation is a useful treatment for patients with DSWI with prosthetic graft infection, resulting in good outcomes, decreased mortality, and decreased recurrent infection rates. 10,11 A previous study reported that NPWT with continuous irrigation improved hospital mortality from 50% to 16.7% in patients with DSWI with prosthetic graft infection. 10 Continuous or intermittent irrigation and drainage contributes to the control of bacterial infections by washing the purulent and necrotic tissues, a strategy termed hydrodebridement.…”

“…8,9 Various salvage treatments for DSWI or DSWI with prosthetic graft infection have been reported. 3,4,[10][11][12][13] The surgical debridement of infected tissues and removal of purulent tissue must be conducted immediately when DSWI with prosthetic graft infection is diagnosed to reduce the bacterial population, control the infection, and ameliorate the patient's condition. NPWT is a standard treatment for patients with DSWI after debridement as it stabilizes the thoracic cage and controls the bacterial infection.…”

“…Saiki et al 14 reported the effectiveness of NPWT for patients with DSWI with prosthetic graft infection. NPWT with continuous or intermittent irrigation is a useful treatment for patients with DSWI with prosthetic graft infection, resulting in good outcomes, decreased mortality, and decreased recurrent infection rates 10,11 . A previous study reported that NPWT with continuous irrigation improved hospital mortality from 50% to 16.7% in patients with DSWI with prosthetic graft infection 10 .…”

“…The use of NPWT with hydrodebridement as a bridge therapy to omental flaps may be an alternative treatment for DSWI with prosthetic graft infection in high‐risk patients. Recently, multidisciplinary strategies including collaboration with a plastic surgeon for proper debridement, NPWT with irrigation, and tissue flaps have been recommended for patients with DSWI with vascular graft infection, as this strategy reduces mortality and has good outcomes 10,11 . Nevertheless, more studies are needed to identify the effectiveness of this enhanced combination therapy for patients with DSWI with prosthetic graft infection, as recurrent infections may occur if the infected prosthetic graft is not removed.…”

Automated Detection of Infection in Diabetic Foot Ulcer Images Using Convolutional Neural Network

“…PAD is another cause of diabetic foot infection; it prevents or slows down the healing process by impairing blood flow. It makes people not feel the initial injury and risk developing foot infection [ 6 ]. Physical examination, blood tests, and a Doppler study of the leg diagnose DFI.…”