Efficacy of Bimatoprost Plus Timolol Fixed Combination in Open Angle Glaucoma Patients Previously Treated with Dorzolamide Plus Timolol Fixed Combination

Sacchi, Matteo; Specchia, Claudia; Williams, Susan E.; Nucci, Paolo

doi:10.3109/02713683.2015.1125507

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…También se ha observado que pueden facilitar el drenaje del humor acuoso, aunque este efecto se considera menos relevante. No obstante, la aparición de nuevos BB como timolol y su combinación con prostaglandinas han mostrado mejores resultados tanto en posología como en adherencia al tratamiento 9 .…”

Section: Discussionunclassified

Propranolol, simultaneous therapeutic effect in a patient. Is there a polypill?

Leiva-Cepas¹,

López-López²,

Chanfreut³

et al. 2017

Actual. Med.

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Propranolol, efecto terapéutico simultáneo en una paciente. ¿Existe la polipíldora? Resumen Ante la presencia de pacientes con diferentes problemas clínicos, el reto para el médico es minimizar al máximo el número de fármacos para conseguir un adecuado cumplimiento terapéutico. Diariamente surgen en el mercado nuevas alternativas farmacológicas que son capaces de conseguir un efecto terapéutico más potente y duradero, reduciendo a su vez los efectos adversos de sus predecesores. Propranolol, es un fármaco ampliamente conocido y empleado para el tratamiento de diversas patologías. La aparición de nuevas opciones en la prevención y tratamiento de eventos cardiovasculares ha disminuido su prescripción en los últimos años y ha favorecido su sustitución en pacientes estables. Como sabemos, es importante hacer una valoración individualizada e integral del paciente ante cualquier modificación de tratamiento. Presentamos el caso clínico de una paciente con múltiples patologías potencialmente graves en la que la suspensión del tratamiento con propranolol fue el desencadenante de la descompensación de su patología de base.

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Section: Discussionunclassified

Propranolol, simultaneous therapeutic effect in a patient. Is there a polypill?

Leiva-Cepas¹,

López-López²,

Chanfreut³

et al. 2017

Actual. Med.

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Cost-effectiveness analysis of iStent trabecular micro-bypass stent for patients with open-angle glaucoma in Colombia

Ordóñez¹,

Ordóñez²,

Osorio

2018

Current Medical Research and Opinion

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From Eye Care to Hair Growth: Bimatoprost

Zeppieri,

Gagliano,

Spadea

et al. 2024

Pharmaceuticals

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Background: Bimatoprost has emerged as a significant medication in the field of medicine over the past several decades, with diverse applications in ophthalmology, dermatology, and beyond. Originally developed as an ocular hypotensive agent, it has proven highly effective in treating glaucoma and ocular hypertension. Its ability to reduce intraocular pressure has established it as a first-line treatment option, improving management and preventing vision loss. In dermatology, bimatoprost has shown promising results in the promotion of hair growth, particularly in the treatment of alopecia and hypotrichosis. Its mechanism of action, stimulating the hair cycle and prolonging the growth phase, has led to the development of bimatoprost-containing solutions for enhancing eyelash growth. Aim: The aim of our review is to provide a brief description, overview, and studies in the current literature regarding the versatile clinical use of bimatoprost in recent years. This can help clinicians determine the most suitable individualized therapy to meet the needs of each patient. Methods: Our methods involve a comprehensive review of the latest advancements reported in the literature in bimatoprost formulations, which range from traditional eye drops to sustained-release implants. These innovations offer extended drug delivery, enhance patient compliance, and minimize side effects. Results: The vast literature published on PubMed has confirmed the clinical usefulness of bimatoprost in lowering intraocular pressure and in managing patients with glaucoma. Numerous studies have shown promising results in dermatology and esthetics in promoting hair growth, particularly in treating alopecia and hypotrichosis. Its mechanism of action involves stimulating the hair cycle and prolonging the growth phase, leading to the development of solutions that enhance eyelash growth. The global use of bimatoprost has expanded significantly, with applications growing beyond its initial indications. Ongoing research is exploring its potential in glaucoma surgery, neuroprotection, and cosmetic procedures. Conclusions: Bimatoprost has shown immense potential for addressing a wide range of therapeutic needs through various formulations and advancements. Promising future perspectives include the exploration of novel delivery systems such as contact lenses and microneedles to further enhance drug efficacy and patient comfort. Ongoing research and future perspectives continue to shape its role in medicine, promising further advancements and improved patient outcomes.

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Efficacy of Bimatoprost Plus Timolol Fixed Combination in Open Angle Glaucoma Patients Previously Treated with Dorzolamide Plus Timolol Fixed Combination

Abstract: BTFC can provide additional lowering in the mean diurnal IOP in patients previously treated with DTFC with no significant differences in the safety and tolerability profile.

Cited by 3 publications

References 29 publications

Propranolol, simultaneous therapeutic effect in a patient. Is there a polypill?

Propranolol, simultaneous therapeutic effect in a patient. Is there a polypill?

Cost-effectiveness analysis of iStent trabecular micro-bypass stent for patients with open-angle glaucoma in Colombia

From Eye Care to Hair Growth: Bimatoprost

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