Efficacy of cyclosporine on mucocutaneous manifestations of Behçet's disease

A Rare Presentation of Behçet Ulcer on the Vaginal Cuff: Case Report

“…Topical anaesthetics, dapsone, sucralfate, granulocyte colonystimulating factor, cyclosporine, topical and intralesional corticosteroids have been used either alone or in combination, having varying degrees of supporting evidence in the treatment of genital ulcers in BS. [19][20][21][22][23] For the topical treatment of genital ulcer and cutaneous lesions, corticosteroid and antiseptic creams can be applied for a short period of time (7 days). Topical sucralfate reduces the healing duration and pain of genital ulcer.…”

Evaluation of patients with Behçet’s disease by cervical cytology and colposcopic examination

“…The majority of the ASCUS results revealed a normal Wnding after cervical histopathology in patients with BD. Immunosuppressive agents including azathioprine and cyclosporin are used in treatments of oral and genital ulcers besides ocular and articular involvement in BD [19,20]. These therapeutic agents may also cause some cellular changes in the cervix or vagina.…”

The use of cyclosporine in dermatology: Part I

“…96,97 Twenty-four patients with mucocutaneous disease were treated with cyclosporine 5 mg/kg/day (reduced to cyclosporine 2.5 mg/kg/day if the serum creatinine increased by 33%) for a minimum of 6 months in an open-label study. 98 This study showed that cyclosporine improved oral ulcerations (18 patients had improvement, with 6 showing no evident oral ulcerations during the treatment period), genital ulcerations (17 of 21 patients had no genital ulcers during the study, one had a reduction in the genital lesions, one had stable disease, and two had worsening), acneiform lesions (17 of 18 patients had no lesions), erythema nodosumelike lesions (17 of 21 patients had no new lesions), and thrombophlebitis-like lesions (6 of 6 patients had resolution). Also, no new ocular attacks were seen in 11 of 14 patients, and arthralgias improved in three of six patients treated with cyclosporine.…”