Efficacy of Distraction Osteogenesis for Mandibular Reconstruction in Previously Irradiated Areas

Kashiwa, Katsuhiko; Kobayashi, Seiichiro; Nohara, Takaya; Yasuoka, Tomoyuki; Hosoya, Yuko; Fujiwara, Hitomi; Honda, Takayuki; Kimura, Hiroaki

doi:10.1097/scs.0b013e3181897351

Cited by 23 publications

(4 citation statements)

References 22 publications

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“…Reconstructive procedures involving the use of cartilage grafts are difficult cases due to lack of blood supply on the recipient bed and donor site requirements necessitate meticulous work. Therefore, in some situations, such as radiotherapy, which cause nutritional deficiencies in cartilage tissue, distraction may be an ideal solution for the repair of the defect as in DO [29,30].…”

Section: Discussionmentioning

confidence: 99%

Distraction Chondroneogenesis On Rabitt's Ear Cartilage

Kocaaslan¹,

Çelebïler²,

Numanoğlu³

et al. 2013

MMJ

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Objective: Application of distraction is an alternative to bone graft or flap operations for repairing bone defects. Bone can be extended in width and length without using a new donor area. Operation time is shortened and failures are reduced without any concern about graft or flap loss. However, there are no distraction methods known for generating new cartilage as an alternative to graft or flap applications in repairs of cartilage defects This experimental study was planned to determine whether or not chondroneogenesis can be obtained via application of distraction. Methods: Fourteen New Zealand rabbits were used in this study. Distractions at a rate of 0.50 mm/day, 0.25 mm/day and 0.25 mm on alternate days were applied on 3 rabbits consecutively and the ideal distraction rate was determined as 0.25 mm once every two days. On alternate days 0.25 mm of distraction was applied for two months aiming to generate 7.5 mm of new cartilage. Results: In the rabbits in which 0.25 mm of distraction on alternate days had been applied, regular new cartilage formation was observed. Conclusions: According to these findings, the slow metabolic rate of avascular cartilage tissue affects distraction rates and rhythms. However, by applying distraction and taking advantage of the regenerative capacity of the perichondrium, it is possible to generate new and regular chondrocytes and extend the cartilage.

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Section: Discussionmentioning

confidence: 99%

Distraction Chondroneogenesis On Rabitt's Ear Cartilage

Kocaaslan¹,

Çelebïler²,

Numanoğlu³

et al. 2013

MMJ

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“…29,30 However, the rare publications about it concern a few cases following cancer treated by interrupted mandibulectomy and radiotherapy, and report difficulties and failures.…”

Section: Bone Distractionmentioning

confidence: 98%

Bone reconstruction in irradiated situations

Froget¹,

Pierrefeu²,

Koppe³

et al. 2011

Preprosthetic and Maxillofacial Surgery

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“…A variation of this with the use of combined iliac crest bone graft has been proposed by several authors [19,25]. Distraction osteogenesis has emerged as a form of autogenous bone replacement for the atrophic mandible as well as for segmental defects [32][33][34] and has even been suggested as a replacement technique for the mandibular condyle [24].…”

Section: Replacement Of the Temporomandibular Jointmentioning

confidence: 99%