Efficacy of first‐trimester ultrasound parameters for prediction of early spontaneous abortion

Datta, Mamta R; Raut, Ankush Nandkishor

doi:10.1002/ijgo.12231

Cited by 32 publications

(19 citation statements)

References 19 publications

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“…Also, similar to the result of Leylek [23] which documented the higher incidence of abortion in cases with low FHR reflecting poor cardiac development. However, some other previous studies had higher cutoff values: [24] showed the best cutoff value of FHR for the continuation of pregnancy was 128 bpm. Dede et al [25] found that an FHR value below 130 bpm had 81.4% sensitivity and 85.1% specificity for predicting abortion.…”

Section: Discussionmentioning

confidence: 83%

Ultrasonography and Pregnancy Outcome in Threatened Abortion: A Prospective Observational Study

Farag¹

2018

Gynecol Obstet

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Aim: To evaluate the role of ultrasound (US) as a predictor of pregnancy outcome in cases with threatened miscarriage. Introduction: First trimester bleeding is a common anxious medical disorder. It may end with pregnancy loss or lead to adverse maternal and fetal outcomes. Certain sonographic parameters like (GSD, YSD, CRL, and FHR) could predict these outcomes. Material and methods: A prospective study involving 500 women in their first trimester was divided into three groups: group I (130 women) in whom threatened abortion ended in abortion, group II (170 women) with threatened abortion and completed their pregnancy and group III (200 women) with normal pregnancy. US indicators included Gestational Sac Diameter (GSD), Yolk Sac Diameter (YSD), Crown-Rump Length (CRL), and Fetal Heart Rate (FHR). These patients were evaluated for the pregnancy outcomes. Results: A significant difference was found between group I and the other two groups regarding FHR and CRL (P<0.05), while no significant difference was observed among the three groups regarding GSD or YSD. Compared to control group, the cases of group II had a higher incidence of premature rupture of membrane PROM (OR=9.9, P<0.05), gestational hypertension (OR=5.4, P<0.05), and placental abruption (OR=4.8, P<0.05). Conclusion: FHR and CRL are good sonographic markers to predict pregnancy outcome in women with threatened miscarriage. FHR at 115 beat/minute yields the best predictivity and CRL at 22 mm yields the least predictive accuracy.

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Section: Discussionmentioning

confidence: 83%

Ultrasonography and Pregnancy Outcome in Threatened Abortion: A Prospective Observational Study

Farag¹

2018

Gynecol Obstet

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“…Addi-tional CA125 detection may increase medical expenses. Ultrasound is commonly used to assess the condition of an embryo [26,27]. However, parameters such as gestational sac diameter (GSD), yolk sac diameter (YSD), crown-rump length (CRL), and heart rate (HR) are difficult to obtain before the pregnancy sac is seen.…”

Section: Discussionmentioning

confidence: 99%

Baseline Levels of Serum Progesterone and the First Trimester Pregnancy Outcome in Women with Threatened Abortion: A Retrospective Cohort Study

Deng

Chen

et al. 2020

BioMed Research International

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Objective. The relationship between serum progesterone and the first trimester pregnancy outcome of threatened abortion is still controversial. Therefore, we aimed to further study the association between these two parameters. Methods. The present study is an observational retrospective cohort study. A total of 726 participants who had threatened abortion from a hospital in Guangdong, China, were included in this study from 17th August 2011 to 30th October 2018. The exposure variable and the outcome variable were serum progesterone measured at baseline and early pregnancy outcome, respectively. Covariates involved in this study included patients' basic demographics, obstetric history, and clinical information. Results. A negative association and a saturation effect were detected between serum progesterone and the first trimester pregnancy outcome. When progesterone <90.62 nmol/L, an increase in 1 nmol/L of serum progesterone was associated with 3% decrease of the risk of miscarriage (OR: 0.97, 95% CI: 0.95-0.98). Conclusion. There was a greater risk of abortion when the serum progesterone level was less than 90.62 nmol/L. Our findings can better assist the clinician in understanding patients' conditions and making medical decisions.

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“…However, certain maternal characteristics, such as the age and body mass index (BMI), have shown to be very informative, with regard to the predicting miscarriage and stillbirth. The risk of preterm delivery is determined by algorithms that combine these results of the first trimester screening for aneuploidy, increased nuchal translucency, the abnormal ductus venosus flow, and low level of PAPP-A, with the characteristics of the mother [7][8][9]. Such example is the information on the length of the cervical canal from 11-to 13-week gestation [9,10].…”

Section: Early Pregnancy Screening Tests and Algorithmsmentioning

confidence: 99%

Implantation and the Fetal Health

Ljubić¹,

Abazović²,

Ljubić³

et al. 2020

Induced Abortion and Spontaneous Early Pregnancy Loss - Focus on Management

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Implantation is one of the crucial periods in human reproduction. Increasing body of evidence suggests that the improper (dysfunctional) implantation and the formation of the placenta can endanger life and health of both the fetus and the mother, during prenatal life and decades after delivery. The idea of the inverted pyramid of prenatal care has emerged in the recent years, as the early detection and prevention of health disorders of the fetus are specially focusing on the first trimester. By applying this principle, disorders in the perinatal period could be prevented or treated with better outcome. The changes that lead to the deficient implantation should be sought in the preimplantation period, in relation between the embryo and the endometrium. It is possible that the time is approaching when the disorders of the pregnancy caused by dysfunctional implantation would be the indication for the application of a natural IVF (without ovarian stimulation) with the use of new biotechnological achievements. For better results of the perinatal medicine, it is necessary to apply earlier (in the preconception and preimplantation periods) the therapy based on the subcellular and genetic level by applying the latest biotechnological procedures.

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Efficacy of first‐trimester ultrasound parameters for prediction of early spontaneous abortion

Abstract: First-trimester ultrasound measurements are predictors of early abortion. Risk assessment tables based on combinations of abnormal measures might improve prediction rates.

Cited by 32 publications

References 19 publications

Ultrasonography and Pregnancy Outcome in Threatened Abortion: A Prospective Observational Study

Ultrasonography and Pregnancy Outcome in Threatened Abortion: A Prospective Observational Study

Baseline Levels of Serum Progesterone and the First Trimester Pregnancy Outcome in Women with Threatened Abortion: A Retrospective Cohort Study

Implantation and the Fetal Health

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