Efficacy of garlic based treatments against monogenean parasites infecting the guppy (Poecilia reticulata (Peters))

Fridman, Sophie; Sinai, Tamar; Zilberg, Dina

doi:10.1016/j.vetpar.2014.02.002

Cited by 71 publications

(47 citation statements)

References 34 publications

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“…Among these, garlic ( Allium sativum ) is one of the most widely used ones. When extracted and isolated, these compounds exhibit a broad spectrum of beneficial effects against microbial infections as well as cardioprotective, anticancerigenic, and anti-inflammatory activity [ 1 – 5 ].…”

Section: Introductionmentioning

confidence: 99%

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

Arreola¹,

Quintero-Fabián

López-Roa

et al. 2015

Journal of Immunology Research

328

217

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The benefits of garlic to health have been proclaimed for centuries; however, only recently have Allium sativum and its derivatives been proposed as promising candidates for maintaining the homeostasis of the immune system. The complex biochemistry of garlic makes it possible for variations in processing to yield different preparations with differences in final composition and compound proportion. In this review, we assess the most recent experimental results, which indicate that garlic appears to enhance the functioning of the immune system by stimulating certain cell types, such as macrophages, lymphocytes, natural killer (NK) cells, dendritic cells, and eosinophils, by mechanisms including modulation of cytokine secretion, immunoglobulin production, phagocytosis, and macrophage activation. Finally, because immune dysfunction plays an important role in the development and progress of several diseases, we critically examined immunoregulation by garlic extracts and compounds isolated, which can contribute to the treatment and prevention of pathologies such as obesity, metabolic syndrome, cardiovascular disorders, gastric ulcer, and even cancer. We concluded that A. sativum modulates cytokine secretion and that such modulation may provide a mechanism of action for many of their therapeutic effects.

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Section: Introductionmentioning

confidence: 99%

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

Arreola¹,

Quintero-Fabián

López-Roa

et al. 2015

Journal of Immunology Research

328

217

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“…The studies on the effects of plant-derived substances on fish parasites have been widely reviewed in the literature (Pic on-Camacho et al 2012;Erguig et al 2015;Wunderlich et al 2017;Tavares-Dias 2018). Anti-parasitic activities of garlic and onion specifying the anti-protozoan, anti-myxozoan and anthelmintic activities were studied in different parasites and fish (Martins et al 2002;Buchmann et al 2003;Pic on-Camacho et al 2012;Fridman et al 2014;Wunderlich et al 2017;Hyun Kim et al 2019). To our knowledge, the anti-crustacean parasite activity of garlic and onion was not studied in aquaculture.…”

Section: Introductionmentioning

confidence: 99%

Anti-parasitic activity of garlic (Allium sativum) and onion (Allium cepa) juice against crustacean parasite, Lernantropus kroyeri, found on European sea bass (Dicentrarchus labrax)

Yıldız

Van

Parisi

et al. 2019

Italian Journal of Animal Science

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The copepod parasite Lernantropus kroyeri impairs the productivity of European sea bass (Dicentrarchus labrax) culture by leading to a direct infection or as a vector for other disease agents. In current conditions, the parasitic infections in mariculture are usually treated with the chemicals, mainly with the pesticides. However, therapeutic chemical use has potential risks on the overall aquatic environment. Thus, the aquaculture sector needs to find alternative substances to the treatment or prophylaxis of the diseases instead of chemicals. In the present study, in vitro exposure tests were performed to elucidate the effects of garlic (Allium sativum) and onion (Allium cepa) on adult L. kroyeri. Female individuals of L. kroyeri were exposed to different concentrations of garlic or onion juice (20, 40, 60, 80 and 100% of the plant juice) for a specified time. Garlic juice exposure at a ratio of 100% resulted in instantaneous death of all individuals in five minutes. Although the killing time varied by the concentration, garlic juice killed the L. kroyeri females within 30 min even at the lowest concentration. Onion juice had lower killing effect at low concentrations, however, higher concentrations of onion juice killed the female parasites within 60 min. Results revealed that garlic and onion juices had killing effect on L. kroyeri females in a time and concentration-dependent manner. It can be concluded that against parasitic copepods alternative solutions can be developed in aquaculture, using these plant juices with emphasising necessity of further in vivo tolerance tests in fish. HIGHLIGHTSGarlic and onion juices had anti-parasitic effect in vitro on the crustacean parasite, Lernantropus kroyeri found on the gills of European sea bass (Dicentrarchus labrax). After exposure of L. kroyeri to garlic and onion juices, the mortality was time and concentration-dependent. The killing activity of garlic juice for L. kroyeri was stronger than that of onion juice. ARTICLE HISTORY

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“…Fridman et al [43] used an aqueous extract of garlic A. sativum in an in vivo assay (30 mL/L), and it caused the separation and decreased movement of two species of monogeneans (Gyrodactylus turnbulli and Dactylogyrus sp.). In the oral (10 and 20%) and bath (7.5 and 12 mL/L) test, the extract showed a significant reduction of parasites when compared to the control group [43].…”

Section: Anthelmintic Activitymentioning

confidence: 99%

Plant-Derived Compounds as an Alternative Treatment Against Parasites in Fish Farming: A Review

Wunderlich¹,

Zica²,

Ayres³

et al. 2017

Natural Remedies in the Fight Against Parasites

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Aquaculture has grown rapidly for food production around the world. However, outbreaks of infectious diseases have also increased in aquaculture, causing serious economic losses. For many years, fish farmers have applied conventional treatments such as anti-parasitics and chemical treatments to control fish parasites. However, previous studies have revealed an accumulation of these chemical residues in fish tissues, and a negative environmental impact from farms to aquatic organisms. As an alternative to conventional methods, many plant-derived compounds such as essential oils (e.g. Origanum sp. and Lippia spp.) and plant extracts (e.g. Allium sativum and Mentha spp.) have been used as an efficient treatment to control parasites in freshwater, brackishwater and marine aquaculture systems. Our objective with this review is to highlight the advantages of the use of plant extracts as an alternative treatment against parasites in aquaculture (e.g. protozoans, myxozoans and monogeneans) and to show the possible negative environmental impacts of conventional treatments used in fish farming systems. Finally, we also highlight the potential of discovering new plant-derived bioactive compounds that have been increased in the last year due to the use of new tools such as the application of nanotechnology and microencapsulation to control diseases in fish farming.

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Efficacy of garlic based treatments against monogenean parasites infecting the guppy (Poecilia reticulata (Peters))

Cited by 71 publications

References 34 publications

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

Anti-parasitic activity of garlic (Allium sativum) and onion (Allium cepa) juice against crustacean parasite, Lernantropus kroyeri, found on European sea bass (Dicentrarchus labrax)

Plant-Derived Compounds as an Alternative Treatment Against Parasites in Fish Farming: A Review

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