Efficacy of honey in reduction of post tonsillectomy pain, randomized clinical trial

Mohebbi, Saleh; Nia, Fatemeh Hasan; Kelantari, Farbood; Nejad, Sheqhayeqh Ebrahim; Hamedi, Yaghoob; Abd, Reza

doi:10.1016/j.ijporl.2014.08.018

Cited by 30 publications

(46 citation statements)

References 12 publications

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“…A point of difference is that, in addition to considering pain during resting and swallowing in the present study, the follow-up period was one week in which 85% of patients in the honey group had no pain or considerably slight pain on the seventh day postoperatively (17). Likewise, Mohebi et al compared the impact of honey on re- duced pain in children after tonsillectomy in honey and control groups and showed that honey was effective in reducing postoperative pain, which is in line with this study; in the former, however, patients received oral honey while in the latter, normal saline mixed with honey was gargled for further contact of honey with the throat mucus (20).…”

Section: Discussionsupporting

confidence: 78%

The Effect of Gargling Cold Normal Saline in Comparison to Normal Saline Mixed with Honey on Postoperative Pain Relief in Tonsillectomy or Adenotonsillectomy: A Randomized Clinical Trial

Raoufian¹,

Nasiri²,

Ghafari³

et al. 2020

Iran Red Crescent Med J

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Objectives: The present study was conducted to compare the effect of gargling normal saline mixed with honey and cold normal saline on postoperative pain relief in children undergoing tonsillectomy or adenotonsillectomy during 2018. Methods: This clinical trial was performed on 105 children aged 5-14 years. The participants were randomly allocated to three 35-member groups, viz. normal saline mixed with honey, cold normal saline, and the control. The patients underwent general anesthesia and then were operated by a single surgeon. Gargle was administered in the first and second groups every six hours up to 48 hours following the surgery. There was no intervention in the control group. The pain was recorded by the Wong-Baker FACES Pain Rating Scale (WBS) at the recovery time and 6, 12, 18, 24, 36, 48 hours and 7 days after the surgery. Data were analyzed using repeated measures ANOVA. Results: Among the participants, 47 subjects (44.8%) were males and the rest were females, with a mean age of 8.6 ± 2.5 years. The three groups were similar in terms of sex, weight, duration of surgery, and bleeding during surgery. The pain at the site of surgery during both resting and swallowing was different at 6, 12, 18, 24, 36, 48 hours, and 7 days following the surgery (P < 0.001). Conclusions: Gargling cold normal saline and normal saline mixed with honey led to reduced pain after tonsillectomy or adenotonsillectomy; however, the latter had a higher effect on the postoperative pain relief.

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Section: Discussionsupporting

confidence: 78%

The Effect of Gargling Cold Normal Saline in Comparison to Normal Saline Mixed with Honey on Postoperative Pain Relief in Tonsillectomy or Adenotonsillectomy: A Randomized Clinical Trial

Raoufian¹,

Nasiri²,

Ghafari³

et al. 2020

Iran Red Crescent Med J

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“…In the pediatric study by Mohebbi et al, patients took much less painkillers when they took honey as the first on-demand medication [17]. The direct comparison with the pain values of other honey studies was not always possible because in the present study a more specific differentiation was made between maximal, minimal and pain in activity.…”

Section: Discussionmentioning

confidence: 73%

“…Studies investigating the effects of honey on tonsillectomy included Tualang honey from Southeast Asia [20,18], unprocessed, pure honey from Malaysia [21], flower honey of thyme and tragacanth plants [16] and commercially available more or less undefined honey [17,29]. Several studies described, that honey application, even on inflamed oral mucosa, is a painless procedure [30,31].…”

Section: Discussionmentioning

confidence: 99%

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The effect of adjuvant oral application of honey in the management of postoperative pain after tonsillectomy in adults: A pilot study

et al. 2020

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Objective To analyze the effect of adjuvant oral application of honey for treating postoperative pain after tonsillectomy. Design Single centre prospective cohort study. Setting Two cohorts of patients after tonsillectomy. Participants 56 patients treated with honey 8 times per day (honey group), 18 patients treated without honey (control group); baseline analgesia were non-steroidal anti-inflammatory drugs (NSAID) or coxibs; opioids were used as pro re nata (PRN) medication; mean age 34.4 ± 13.4 years; 36% women. Main outcome measures On first to fifth postoperative day, patients rated their pain using the validated questionnaire of the German-wide project Quality Improvement in Postoperative Pain Treatment (QUIPS) including a numeric rating scale (NRS, 0-10) for determination of patient's pain. QUIPS allows standardized assessment of patients' characteristics andpain-associated patientreported outcomes (PROs). The influence of preoperative and postoperative parameters on patients' postoperative pain were estimated by univariate and multivariate statistical analysis.

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“…The p value is >0.05. 7 Hebbi et al quoted that Honey administration after tonsillectomy has valuable effect in pain relief and it can be used as an adjunctive regimen after surgery for better pain control. In their study it was observed that Pain comparison between two groups showed that the average time required for pain relief in patients who received honey was less than the control.…”

Section: Bar Diagram Showing Mucosal Healing In Group a And B N=78: 2x39mentioning

confidence: 99%

Post - Operative Pain Management of Tonsillectomy Patients; Clinical Evaluation of Using Oral Honey in 78 Patients

A¹,

Ahmed²,

S³

et al. 2015

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Efficacy of honey in reduction of post tonsillectomy pain, randomized clinical trial

Cited by 30 publications

References 12 publications

The Effect of Gargling Cold Normal Saline in Comparison to Normal Saline Mixed with Honey on Postoperative Pain Relief in Tonsillectomy or Adenotonsillectomy: A Randomized Clinical Trial

The Effect of Gargling Cold Normal Saline in Comparison to Normal Saline Mixed with Honey on Postoperative Pain Relief in Tonsillectomy or Adenotonsillectomy: A Randomized Clinical Trial

The effect of adjuvant oral application of honey in the management of postoperative pain after tonsillectomy in adults: A pilot study

Post - Operative Pain Management of Tonsillectomy Patients; Clinical Evaluation of Using Oral Honey in 78 Patients

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