Efficacy of Intermittent Normobaric Hypoxic Training in the Treatment of Arterial Hypertension Assessed by 24-Hour Blood Pressure Monitoring

Velizhanina, I. A.; Gapon, L.; Евдокимова, О. В.; Velizhanina, E. S.; Rudakov, A. V.

doi:10.17816/clinpract8451-55

Journal of Clinical Practice

2017

DOI: 10.17816/clinpract8451-55

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Efficacy of Intermittent Normobaric Hypoxic Training in the Treatment of Arterial Hypertension Assessed by 24-Hour Blood Pressure Monitoring

I. A. Velizhanina¹,

L. Gapon²,

О. В. Евдокимова³

et al.

Abstract: The study performs the results of our own researches regarding the method of intermittent normobaric hypoxic training as drug-free treatment in patients with arterial hypertension with low risk of cardiovascular complications. Clinical efficacy was assessed according to office blood pressure changes using dynamic 24-hour blood pressure monitoring before and after treatment. High clinical efficacy and safety of hypoxic training method is demonstrated in this work.

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Influence of complex cardio-respiratory recovery therapy on the efficiency of rehabilitation and quality of life on hypertensive patients with chronic obstructive pulmonary disease of dust etiology

Ignatenko,

Mukhin,

Sochilin

et al. 2023

Journal of Volgograd State Medical University

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The aim of the study was to analyze the effect of two rehabilitation regimens on the effectiveness and quality of life in hypertensive patients with dusty chronic obstructive pulmonary disease (COPD). The study included 73 hypertensive patients (all men) with dust COPD. Patients of group 1 (n = 38) received only the basic cardio-respiratory complex of rehabilitation measures, and the representatives of group 2 (n = 35) received sessions of interval normobaric hypoxic therapy (INBHT) in addition to the basic complex. The control group included 40 practically healthy men of the same age. The basic program included a set of methods: electrosleep, magnetotherapy, sinus module currents, diadynamic currents, franklinization, darsonvalization, laser therapy, electrophoresis, kinesitherapy, massage, reflexotherapy. For INBHT, daily 15-day sessions were used in the Bio-Nova 204AF installation (manufactured by the Scientific and Technical Association Bio-Nova, Moscow, Russia). Statistical data processing was carried out using the software package for statistical analysis Statistica 6.0. The result of a comprehensive cardio-respiratory rehabilitation program was an increase in the effectiveness of restorative measures and an improvement in quality of life indicators, which was achieved through the synergistic effect of traditional approaches with INBHT sessions. Such a comprehensive program had a more pronounced beneficial effect on both the course of hypertensive and respiratory syndromes. The proposed rehabilitation approach can further improve the effectiveness of restorative measures (by 13.1 % increase the frequency of positive results), increase the frequency of reaching the target level of blood pressure by 9.7 %, reduce the frequency of complicated and 7.9 % uncomplicated hypertensive cases by 4.1 %. Crises, improve bronchial patency and diffusion capacity of the lungs, partially restore the complex of psychological, social and pain parameters of the quality of life.

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Influence of complex cardio-respiratory recovery therapy on the efficiency of rehabilitation and quality of life on hypertensive patients with chronic obstructive pulmonary disease of dust etiology

Ignatenko,

Mukhin,

Sochilin

et al. 2023

Journal of Volgograd State Medical University

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Treatment potential of normobaric hypoxic therapy in therapeutic and pediatric practice

Игнатенко

Dubovaya

Naumenko

2023

Ross. vestn. perinatol. pediatr.

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Normobaric hypoxic therapy is a therapeutic or prophylactic use of gas hypoxic mixture containing 10% oxygen and 90% nitrogen, alternating with breathing atmospheric air at normal barometric pressure. The use of normobaric hypoxic therapy allows activating and using genetically programmed mechanisms aimed at increasing the nonspecific resistance of the body. The history data, pathogenesis of normobaric hypoxic therapy, the procedure and its effect on the cardiovascular system are described.

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Treatment of cardiotoxicity in patients with invasive breast cancer during neoadjuvant chemotherapy

Ignatenko,

Sedakov,

Kolycheva

et al. 2024

Science and Innovations in Medicine

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Aim– assessment of the effectiveness of complex therapy to reduce the development of early cardiovascular complications. Materials and methods. Information from medical histories and outpatient follow-up cards of 139 patients with invasive breast cancer was analyzed: in the G.V. Bondar Republican Cancer Center 64 patients (main and control groups); as an additional comparison group, the study included 75 patients of the State Budgetary Healthcare Institution “Samara Regional Clinical Oncology Dispensary”. Patients in the control group (33 people) and the Samara Regional Clinical Oncology Dispensary group (75 people) received standard therapy (RUSSCO, recommendations, 2023): doxorubicin 60 mg/m2 IV on day 1 + cyclophosphamide 600 mg/m2 IV on day 1 Day 4 - 4 courses. In 31 patients of the main observation group, in addition to similar drug treatment, in order to prevent the development of early cardiovascular complications, the method was used, which included 7 courses before the start of 1 cycle of chemotherapy + 3 courses of interval normobaric hypoxic therapy (INHT) before the start of each subsequent cycle of chemotherapy. Results. When analyzing the total effectiveness of treatment between the groups of patients, statistically significant differences were obtained: the control and main groups were compared (χ2=5.4, p=0.03), the group of the Samara Regional Clinical Oncology Dispensary group and the main group (χ2=3.45, p=0.076). Conclusions. Hypoxic therapy significantly affects the quality of life of patients. For all indicators reflecting quality of life, traditional treatment was inferior to combination drug therapy with INHT.

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Efficacy of Intermittent Normobaric Hypoxic Training in the Treatment of Arterial Hypertension Assessed by 24-Hour Blood Pressure Monitoring

Cited by 3 publications

References 0 publications

Influence of complex cardio-respiratory recovery therapy on the efficiency of rehabilitation and quality of life on hypertensive patients with chronic obstructive pulmonary disease of dust etiology

Influence of complex cardio-respiratory recovery therapy on the efficiency of rehabilitation and quality of life on hypertensive patients with chronic obstructive pulmonary disease of dust etiology

Treatment potential of normobaric hypoxic therapy in therapeutic and pediatric practice

Treatment of cardiotoxicity in patients with invasive breast cancer during neoadjuvant chemotherapy

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