This chapter explores the use of smart materials in physiotherapy, highlighting their potential to revolutionize patient care and rehabilitation practices. It discusses various types of smart materials, such as shape memory alloys, electroactive polymers, piezoelectric materials, magnetorheological materials, and thermoresponsive polymers, and their unique properties and applications. The chapter also discusses the use of smart materials in assistive devices, wearable technology, rehabilitation, pain management, and tissue healing. The advantages of smart materials include personalization, real-time monitoring capabilities, and non-invasive nature. However, challenges such as cost, integration with existing healthcare systems, and durability concerns need to be addressed. The chapter concludes by exploring future advancements in smart materials, integrating them with other technologies like AI, robotics, and nanotechnology. Ethical considerations and patient acceptance are also emphasized to ensure responsible and patient-centric adoption.