Efficacy of Sri Lankan traditional decoction of Katuwelbatu Deduru Katukadi in treatment of Kaphaja Shira Shula (chronic sinusitis)

Ediriweera, E.R.H.S.S.; Rathnayaka, R.L.Y.U.; Premakeerthi, W.M.S.A.; Weerasinghe, Kaveen

doi:10.4103/0974-8520.68208

Cited by 7 publications

(15 citation statements)

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“…Inclusion criteria were not the same in the four trials. Two studies, by Ediriweera (Ediriweera, Rathnayaka, Premakeerthi, & Weerasinghe, ) and Maragalawaththa (Maragalawaththa, Ediriweera, & Chandimarathne, ), were based only on clinical symptoms as reported by patients without any standard questionnaire. The other two studies (Jiang [20] and Vazifehkah [23]) used diagnostic criteria based on the European position paper on rhinosinusitis and nasal polyps (EPOS) and sinus endoscopy.…”

Section: Resultsmentioning

confidence: 99%

A systematic review of randomized controlled trials with herbal medicine on chronic rhinosinusitis

Anushiravani

Bakhshaee

Taghipour

et al. 2017

Phytotherapy Research

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Chronic rhinosinusitis (CRS) is a common disease with evidence to show that its incidence and prevalence are increasing. Medicinal plants are commonly used to treat CRS. This systematic review aimed to assess the effectiveness and safety of herbal preparations for treatment of the patients with CRS. Cochran, Embase, ISI, PubMed, and Scopus databases were searched until August 1, 2016. Only randomized controlled trials were included. Four randomized controlled trials were included in this systematic review. Various medicinal plants were studied in each article. Inclusion and exclusion criteria, and outcome measures varied among different articles. The results of this trials showed that this special medicinal plants may be effective in the treatment of CRS. No serious reactions were reported during the administration of herbal remedies in the 4 studies. However, trials with a well-designed approach are needed to study the actual safety and efficacy of herbs in the treatment of CRS.

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Section: Resultsmentioning

confidence: 99%

A systematic review of randomized controlled trials with herbal medicine on chronic rhinosinusitis

Anushiravani

Bakhshaee

Taghipour

et al. 2017

Phytotherapy Research

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“…Among these 10 selected comparative clinical trials (pre-treatment n = 387; end of treatment n = 363) [13,14,15,16,17,18,19,20,21,22], 8 were RCTs and 02 were nRCTs. Out of these 10 trials, 5 RCTs and 2 nRCTs were included in quantitative analysis (pre-treatment n = 287; end of treatment n = 259).…”

Section: Resultsmentioning

confidence: 99%

“…Out of these 10 trials, 5 RCTs and 2 nRCTs were included in quantitative analysis (pre-treatment n = 287; end of treatment n = 259). Among them, 4 trials were having three arms and 3 trials were having two arms and blinding was reported in only one trial[22]. However, none of the trials mentioned concealment methods.…”

Section: Resultsmentioning

confidence: 99%

“…The mean participants in each arm of the trials were found to be 16. All the selected studies were conducted in the outpatient department(OPD) and inpatient department(IPD) of different Ayurveda college hospitals and research institutes of India except one[22], which was conducted in Srilanka. Heterogeneity was observed in the included study population(diagnosis), treatment protocol, and follow-up duration.…”

Section: Resultsmentioning

confidence: 99%

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Efficacy and safety of Ayurveda interventions for Sinusitis: A systematic review and meta-analysis

Ahmad

Gundeti

Dave

et al. 2021

Preprint

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Objectives To provide a broad evaluation of the efficacy and safety of Ayurveda interventions (procedural and non-procedural) for the management of sinusitis, and also of the relative efficacy and safety of different Ayurveda therapies for Sinusitis. Methods: Two reviewers independently screened search results from electronic databases viz. Cochrane Library, PubMed(central), AYUSH Research Portal, and DHARA for published research articles and Shodhganga, RGUHS library, and ARD-IPGT&RA for the unpublished doctoral thesis. Trial registries (CTRI, Clinicaltrials.gov & WHO-ICTRP), and hand searches were also done for other relevant studies from inception to August 2020. All comparative clinical trials recruiting sinusitis patients of any age group, receiving Ayurveda intervention, regardless of forms, dosages, ingredients, and mode of interventions, for not less than one week were included. The data extraction and the risk of bias assessment were done by two reviewers independently. Protocol registration number: RD42018103995. Results We included 10 trials (387 participants) for qualitative analysis and 07 trials (287 participants) for quantitative analysis. Ayurveda intervention demonstrated potential in reducing signs and symptoms of sinusitis compared with placebo (Risk Ratio ranges 6.33 to 12.67, 1 trial, 80 participants). Combined Ayurveda therapy (CT) was statistically more beneficial compared with either procedural or non-procedural Ayurveda therapy alone in reducing symptoms nasal discharge (standardized MD -0.71, 95% CI -1.16 to -0.26, I2 58%, 10 comparisons, 210 participants) and headache (standardized MD -0.44, 95% CI -0.86 to -0.02, I2 56%, 10 comparisons, 218 participants), however, no significant difference was found in reducing symptoms nasal obstruction and loss of smell. Also, there was no significant difference found in similar outcomes while comparing Ayurveda procedural therapy with non-procedural therapy. No numerical data related to the safety of Ayurveda intervention was found in included trials. Conclusions Despite very low certainty in results (downgraded twice for RoB, once for inconsistency, indirectness, and imprecision each), Ayurveda intervention (CT) may have some beneficial effects in the management of Sinusitis. However, due to insufficient data, we could not conclude on the safety aspect. There is a need for well-designed-executed-reported clinical studies for the generation of evidence. Keywords Ayurveda, Systematic Review, Meta-analysis, Sinusitis, Rhinosinusitis, Pratishyaya, Peenasa.

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“…Royal jelly, grapes, and figs are also reinforcing the brain and the nervous system (17)(18)(19)(20). The positive effects of cumin (C. cyminum) and black cumin (N. sativa) on the treatment of vertigo, sinusitis, and post nasal discharge are expressed in numerous articles (21,22). Coriander is also used in Ayurveda as a CNS tonic to treat vertigo (23,24).…”

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confidence: 99%

Treatment of Meniere’s Disease with Persian Medicine: A Case Report

2018

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Introduction: Meniere's disease is one of the most common inner ear and vestibular disorders. Its conventional treatment gives unsatisfying results in some cases. This article introduces a patient with Meniere's disease who has been treated with Persian medicine. Case Presentation: The patient was a 40-year-old woman, a known case of Meniere's disease, who was advised to consume cinnarizine and betahistine. Due to lack of satisfactory response to treatment, the patient referred to Persian medicine clinic. She followed the recommendations of Persian medicine and the disease was completely recovered. Conclusions: Treatment of Meniere's disease in this patient was based on lifestyle modification, warming up the body, strengthening the brain and the nervous system, enhancing the digestive system, modifying the condition of defecation, and removing waste materials and accumulated humors from the body, especially the head. It is believed that this case report will provide a basis for further studies on the impact of Persian medicine on the treatment of Meniere's disease.

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Efficacy of Sri Lankan traditional decoction of Katuwelbatu Deduru Katukadi in treatment of Kaphaja Shira Shula (chronic sinusitis)

Cited by 7 publications

References 0 publications

A systematic review of randomized controlled trials with herbal medicine on chronic rhinosinusitis

A systematic review of randomized controlled trials with herbal medicine on chronic rhinosinusitis

Efficacy and safety of Ayurveda interventions for Sinusitis: A systematic review and meta-analysis

Treatment of Meniere’s Disease with Persian Medicine: A Case Report

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