Introduction: A resurgence of interest in Ayurveda, other traditional systems of medicine, and complementary and alternative medicine (CAM) has resulted from the preference of many consumers for products of natural origin. The potential benefits of plant-based medicines could lie in their high acceptance by patients, and efficacy and safety. The most prevalent users of traditional medicine are individuals who have refractory conditions and nonlife-threatening conditions that may be chronic viz. neurological disorders, arthritis, etc. The second-largest group of users is those struggling with chronic, potentially life-threatening diseases, such as cancer and human immunodeficiency virus/acquired immunodeficiency syndrome, etc. Both groups turn to Ayurveda and traditional system of medicine for a variety of reasons, such as management as the main treatment option and improved immune functioning, overall functioning, and quality-of-life (QoL) by coping with side effects from conventional therapies, and to relieve symptoms related to their illness. The upsurge in use of traditional system among cancer patients warrants evidence of safety and effectiveness for these interventions as concomitant to conventional cancer therapy.

Ardhavabhedaka-hemicranial headache is a psychosomatic disorder: later replaced by migraine a Greek word "half of the head" because the pain of migraine often occurs on one side(classical Migraine) may affect the entire head. The term "migraine" refers to a syndrome of vascular pathology of the cranial blood vessels and is one of the commonest headache encountered in clinical practise. The survey results suggested that both patients and physicians believe migraine treatment is elusive and that patients are becoming increasingly frustrated and dissatisfied with treatment outcomes. Clinically, it is a Rakta/Pitta dominant disease;andAcharya Charaka opined that the vitiated Doshas after reaching Shirah vitiates Rakta (Rasavaha and Raktavaha Srotas) there to produce Shiro Roga (headache). Its diagnosis is based on mainly clinical history. For the present study, it was planned to compare the result between Brihat Jeevakadhya Taila Nasyaand Sutashekhara Rasa orally (Pitashamaka, Raktashodhaka, Deepana etc.) in Treatment Trial group and Flunarizine in Control group. The overall effect of therapy showed that in Trial group 80. 00% patients had marked improvement, followed by moderate improvement in 13. 33% and complete improvement in 6. 67%. In control group marked and moderate improvement was seen in 60. 00% and 33. 33% respectively; and 6. 67% had mild improvement. No any adverse drug reaction was found during whole study. Total 30 patients were registered and from the results and observation which were received from this study it can be concluded that Trial group is showing better results in Ardhavabhedaka

Introduction: A systematic review is planned to investigate the safety and efficacy of Ayurveda interventions for hepatitis through analyzing published clinical research work. Materials and methods: We shall conduct a systematic review published clinical work for Ayurveda interventions for hepatitis. Electronic search of following databases will be performed: PubMed, AYUSH Research Portal, Digital Helpline for Ayurveda Research Articles (DHARA), Google Scholar, the Cochrane Library (the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials (CENTRAL), and the Cochrane Methodology Register) without any restriction of publication year. Hand search, snowballing of studies will also be performed to fetch complete available literature. The selection of the studies, data abstraction, and validations will be performed independently by two teams of researchers. A conclusion will be derived from the consensus of the complete review team. Study selection will follow the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines and study quality will be assessed by the CONSORT checklist for randomized controlled trials (RCTs), transparent reporting of evaluations with nonrandomized designs (TREND) checklist for nonrandomized controlled trials (NRCTs), and CONSORT extension for pilot and feasibility studies for pilot studies. Risk of bias assessment will be performed with the help of the Cochrane risk-of-bias tool for randomized trials (RoB2) tool for RCTs and risk of bias in nonrandomised studies of interventions (ROBINS-I) tool for NRCTs. If sufficient and appropriate data are available, a meta-analysis will be conducted. Subgroup analysis and sensitivity analysis will be performed if found to be necessary and feasible. Dissemination: The systematic review will be published in a peer-reviewed journal. The review will also be disseminated electronically and in print. The review will be updated to inform and guide healthcare practice and policy. Trial registration number: PROSPERO 2019: CRD42019103115.

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Background: Allergic rhinitis is one of the most common and most prevalent ailments, familiar to all with an equal distribution more or less throughout the world, rather without any exception to the developed and under developed countries. Repeated attack and improper management of the disease leads to many complications like recurrent sinusitis, nasal polyps, serous otitis media, orthodontic problems etc. Objective: To evaluate the role of Ayurvedic Formulations in the management of Allergic rhinitisMaterials and methods: The study was executed as on open label, multicentric, prospective clinical study executed at (CARI, New Delhi and CARI, Mumbai). Sixty participants aged between 18 and 65 years, having the symptoms of Allergic rhinitis were enrolled in the study as per the inclusion and exclusion criteria. The intervention given to the participants were Ayush VPR (3.5gm) in the form of Churna (powder) twice a day with honey and Ghrita (clarified butter) after food, Shirishadi Kwath (20 ml) twice a day, orally in empty stomach and Nasya (intranasal drug administration) with Anutaila for 07 days for two consecutive cycles with the interval of seven days. The assessment was done every week. Total duration of intervention was 28 days followed by follow up of 28 days on the interval of 14 days. The primary outcome was assessed by seeing the change in the CARAT (Control of Allergic Rhinitis and Asthma Test) scorewith Mauchly’s test of sphericity (b).Results: The mean CARAT score was found to reduce subsequently from baseline to 7th, 14th, 21st and 28th day. A significant improvement in the mean total CARAT score (p < 0.001) was observed after 28th day of treatment and also at the end of the 56th day in comparison to baseline (Mauchly's Test of Sphericity (b) Measure) Conclusion: The Ayurvedic formulations, Shirishadi Kwath, Ayush VPR and Anutaila are safe and significantly reduced rhinorrhea, nasal itching, Sneezing fits, nasal congestion, and nasal obstruction. The present study reveals that Ayurvedic treatment according to the line of treatment of Vataja Pratishyaya provided highly significant relief from Allergic rhinitis.