Ardhavabhedaka-hemicranial headache is a psychosomatic disorder: later replaced by migraine a Greek word "half of the head" because the pain of migraine often occurs on one side(classical Migraine) may affect the entire head. The term "migraine" refers to a syndrome of vascular pathology of the cranial blood vessels and is one of the commonest headache encountered in clinical practise. The survey results suggested that both patients and physicians believe migraine treatment is elusive and that patients are becoming increasingly frustrated and dissatisfied with treatment outcomes. Clinically, it is a Rakta/Pitta dominant disease;andAcharya Charaka opined that the vitiated Doshas after reaching Shirah vitiates Rakta (Rasavaha and Raktavaha Srotas) there to produce Shiro Roga (headache). Its diagnosis is based on mainly clinical history. For the present study, it was planned to compare the result between Brihat Jeevakadhya Taila Nasyaand Sutashekhara Rasa orally (Pitashamaka, Raktashodhaka, Deepana etc.) in Treatment Trial group and Flunarizine in Control group. The overall effect of therapy showed that in Trial group 80. 00% patients had marked improvement, followed by moderate improvement in 13. 33% and complete improvement in 6. 67%. In control group marked and moderate improvement was seen in 60. 00% and 33. 33% respectively; and 6. 67% had mild improvement. No any adverse drug reaction was found during whole study. Total 30 patients were registered and from the results and observation which were received from this study it can be concluded that Trial group is showing better results in Ardhavabhedaka

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Ardhavabhedaka defines Ardha Mastak Vedana. The word migraine is derived from the Greek word hemicranias, meaning "half of the head". Migraine is now recognized as a chronic illness, not simply a headache. Many medications have been tried and a lot are still in research work also, but modern drugs are not acceptable due to their drawbacks. In contrast to that Ayurveda has a variety of natural medication in the treatment of Ardhavabhedaka. It was planned to compare the result between Laghu Sutashekhara Rasa orally in Group A, Brihat Dashamoola Taila Nasya in Group B, placebo drug in Group C and Go-ghrita Nasya in Group D. The overall effect of therapy showed that in Group A 38% patients cured and 36% patients got marked improvement. In Group B 46.67% patients moderately improved and 35.55% patients marked improved. In Group C 90% patients unchanged. In Group D 48.89% patients moderately improved and 28.89% patients marked improved. No any adverse drug reaction was found during whole study. Total 150 patients were registered and from the results and observation which were received from this study it can be concluded that Group A is showing better results in Ardhavabhedaka.Â

Introduction: Potency of drug is termed as Virya of Ausadhi (effectiveness of drug) and the time period, where it retains the potency is known as Saviryata Avadhi. Every product has definite shelf life that depends on physical, chemical, environmental and biological factors. Though, shelf life of various categories of āyurvedic medicines is available; there is a need to revalidate the shelf life of individual formulations by following parameters prevalent in respective scenario. Trivrit Avaleha is mentioned in Astanga Hridaya for Virecana (therapeutic purgation). Aim of the current study is to evaluate shelf life of Trivrit Avaleha (TA) with the help of modern analytical techniques. Methods: Physico-chemical parameters were measured at 40°C ± 2°C temperature and 75%±5% relative humidity. Analysis was repeated at intervals of 1, 3, and 6 months and average 10% degradation of the test drug samples was calculated and extrapolated to find the shelf life. Results: Product was found to be free from microbial contamination and heavy metals were within the permissible limits. There were insignificant changes in physico-chemical profiles at different intervals of analysis. On extrapolation of the observations, the shelf life of TA was found to be 1 year and 11 months. Conclusion: Shelf life of TA is found within the standards of Gazettes of Govt. of India as well as Sarandhara Samhitā.

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