Background Laghu Sutashekhara Rasa (LSR) is a herbo mineral formulation containing Shuddha Gairika (Fe 2 O 3 ) and Shunthi ( Zingiber officinale Roxb.) with the levigation of Nagawalli Swarasa (fresh juice of Piper betel Linn.) prepared as per the reference of Rasatarangini Parishistha . This is an important formulation in Ayurveda therapeutics, but its shelf life is not evaluated till date. The Govt. of India Gazette specifies the shelf life of various Ayurvedic medicines. However, there is a need to revalidate the shelf life of individual formulations by following parameters prevalent in respective scenario. Objectives To evaluate shelf life of Laghu Sutashekhara Rasa. Materials and methods Laghu Sutashekhara Rasa was prepared in the Pharmacy, Gujarat Ayurved University, Jamnagar following classical guidelines. The samples were subjected to accelerated stability study maintaining temperature and humidity 40 ± 2 °C and 75 ± 5% respectively. Relevant analytical parameters were analyzed at an interval of 0, 1, 3 and 6 months to check the degradation levels in the formulation. Result Product was free from microbial contamination and heavy metals were within the prescribed limits. There were insignificant changes in physico-chemical profiles at different intervals of analysis. On extrapolation of the observations, the shelf life of Rasayoga was found to be 2 years and 8 months. Conclusion The shelf life of Laghu Sutashekhara Rasa was found to be less than the given standards in official gazettes of Govt. of India. This decreased shelf life may be because of the predominantly (approximately 70%) herbal component present in the formulation.

Introduction: Potency of drug is termed as Virya of Ausadhi (effectiveness of drug) and the time period, where it retains the potency is known as Saviryata Avadhi. Every product has definite shelf life that depends on physical, chemical, environmental and biological factors. Though, shelf life of various categories of āyurvedic medicines is available; there is a need to revalidate the shelf life of individual formulations by following parameters prevalent in respective scenario. Trivrit Avaleha is mentioned in Astanga Hridaya for Virecana (therapeutic purgation). Aim of the current study is to evaluate shelf life of Trivrit Avaleha (TA) with the help of modern analytical techniques. Methods: Physico-chemical parameters were measured at 40°C ± 2°C temperature and 75%±5% relative humidity. Analysis was repeated at intervals of 1, 3, and 6 months and average 10% degradation of the test drug samples was calculated and extrapolated to find the shelf life. Results: Product was found to be free from microbial contamination and heavy metals were within the permissible limits. There were insignificant changes in physico-chemical profiles at different intervals of analysis. On extrapolation of the observations, the shelf life of TA was found to be 1 year and 11 months. Conclusion: Shelf life of TA is found within the standards of Gazettes of Govt. of India as well as Sarandhara Samhitā.

Background: Lekhaniya Mahakashaya Siddha Taila (LMST) is a herbal formulation containing 10 herbal drugs, i.e., Lekhaniya Mahakashaya Gana mentioned in the Charak Samhita Shadvirechana Shatashritiya chapter. This is an important formulation in Ayurveda therapeutics, but its shelf life is not evaluated till date. The Government of India Gazette specifies the shelf life of various Ayurvedic medicines. However, there is a need to revalidate the shelf life of individual formulations by following parameters prevalent in the respective scenario. Considering this, it is planned to evaluate the shelf life of LMST. Materials and methods:Taila was prepared following classical guidelines. The samples were subjected to the accelerated stability study maintaining temperature and humidity 40 ± 2 °C and 75 ± 5%, respectively. Relevant analytical parameters were analyzed at an interval of 0, 1, 3, and 6 months to check the degradation levels in the formulation. The 10% degradation was set as the acceptable point to extrapolate the accelerated stability data. Real-time aging factors 5 and 3.3 were used for the extrapolation of shelf life for climatic zone I and II countries and climatic zone III and IV countries, respectively. India comes under climatic zones III and IV. The formula for the calculation of shelf life given in the manuscript and International Council for Harmonisation (ICH) guidelines are used for conducting the shelf life study. Results:The microbial contamination and heavy metals were found to be within the prescribed limits. There were insignificant changes in physicochemical profiles at different intervals. On extrapolation of the observations, the shelf life of Taila was found to be 4 years. Conclusion:The shelf life of LMST was found to be longer than the given standards in official Gazettes of Government of India. This observation may be exclusive to LMST. Studies on other Tailas need to be carried out to confirm this preliminary observation.

It is accepted by everyone that Ayurveda is an ancient most literature in medical world. In the early period of Samhita the traces of survey can be seen mainly aiming to the prevention of people suffering from various diseases. Survey is the way by which one can present the classical facts and directives in more practical manner to the current society. Upapluta Yonivyapad is one of the 20 Yonivyapad described by Acharyas. On the basis of the textual description Upapluta Yonivyapad can be compared to vulvovaginitis during pregnancy. Here, Survey study was aimed to elicit etiopathogenesis and prevalence of Upapluta Yonivyapad   in and around Jamnagar city. The Study was conducted on 200 pregnant women attending the OPD of SRPT Dept. (I.P.G.T. & R.A.), Jamnagar, of whom 100% cooperated to give vaginal smear samples to microbiology laboratory. Organisms like gram negative bacteria and yeast were found in (92.5%) and (17.5%) of cases respectively. Etiological factors like Vishamashana in (49%) of cases, Divaswapa (day sleep) in (74.5%), excessive intake of Madhura Rasa in (68.5%) and Ati-Vyavaya (Excessive coitus) in (58%) were observed. Survey questionnaire shows that certain dietary and life style factors contribute towards occurrence of Upapluta Yonivyapad   in maximum i.e. 56.5% of patients.

Infertility is defined as failure to conceive within one year or more than one year of regular & unprotected coitus. It is the most sensitive and cumbersome problem which haunts every couple. Total 10-15% of world population affected due to this problem. Among them Female is directly responsible about 40%. The sub factors of female infertility are Ovarian, Endometrial, Tubal and Uterine etc. In Ayurved so many formulation are given for Infertility. Phalakalyana Ghrita (PKG) is a commonly used and prescribed Ayurvedic poly herbal formulation in all types of Infertility. However, till date no published data is available on its analytical profile. The main aims and objectives of this study are to develop the pharmacognostical and phytochemical profile of PKG. The pharmacognostical study reveals the presence of Lignified fibres, Prismatic crystals, Borderpitted vessels, Rhomboidal crystal, Scleroids, Stone cells etc. Pharmaceutical analysis showed that the loss on drying value was 0.47% w/w, Specific gravity was 0.9133, Refractive index was 1.46, Iodine value was 48.56, Saponification value was 227.05, and Acid value was 1.29. HPTLC fingerprinting profile of PKG revealed 10 spots at 254 nm and 5 spots at 366nm.