Infertility is defined as failure to conceive within one year or more than one year of regular & unprotected coitus. It is the most sensitive and cumbersome problem which haunts every couple. Total 10-15% of world population affected due to this problem. Among them Female is directly responsible about 40%. The sub factors of female infertility are Ovarian, Endometrial, Tubal and Uterine etc. In Ayurved so many formulation are given for Infertility. Phalakalyana Ghrita (PKG) is a commonly used and prescribed Ayurvedic poly herbal formulation in all types of Infertility. However, till date no published data is available on its analytical profile. The main aims and objectives of this study are to develop the pharmacognostical and phytochemical profile of PKG. The pharmacognostical study reveals the presence of Lignified fibres, Prismatic crystals, Borderpitted vessels, Rhomboidal crystal, Scleroids, Stone cells etc. Pharmaceutical analysis showed that the loss on drying value was 0.47% w/w, Specific gravity was 0.9133, Refractive index was 1.46, Iodine value was 48.56, Saponification value was 227.05, and Acid value was 1.29. HPTLC fingerprinting profile of PKG revealed 10 spots at 254 nm and 5 spots at 366nm.

Infertility is the most sensitive and cumbersome problem which haunts every couple. The major cause in infertility is female factor which is 30.20%. Among female factor the sub factors are ovarian, tubal, endometrial and uterine. Female Infertility due to tubal blockage is the 2nd most contributing factor, in 30% of the cases. So for this study, we considered only tubal infertility and to make a pin-pointed assessment criteria. The criteria for selection of patients and assessment of results were unilateral or bilateral tubal blockage diagnosed in hysterosalpingography (HSG).  Thus 18 patients in the age group of 20-40 years were registered for the study, with 75% primary infertility and 25% secondary infertility. Of these patients 16 completed the course of treatment. Patients having acute pelvic infection, hypersensitivity to chemical dye, congenital anomalies of vulva & vagina, CA cervix, STD or any debilitating diseases like T.B. were excluded. Apamagra Kshara Taila was selected for its Vata-Kapha Shamaka and Lekhana properties. The dose of Uttar Basti was 5 ml with duration of two consecutive cycles at the interval of three days. The tubal blockage was removed in 75% of the patients and 25% of the patients had conceived within the follow-up period of two months. The results suggest that Uttar Basti is a safer, cost effective and highly significant Ayurvedic treatment modality for tubal-blockage, with no apparent complications.