Efficacy of sticky bone as a novel autologous graft for mandibular third molar extraction socket healing - An evaluative study

Abstract

Introduction: Recently, initiation and enhancement of extraction socket healing has been amplified by platelet concentrates, whereas the positive role of Sticky bone has been focused on maintaining alveolar bone dimensions. This study aimed to determine the effectiveness of Sticky Bone for socket grafting of mandibular third molars (M3Ms) in terms of soft- and hard-tissue healing. Materials and Methods: This split-mouth prospective trial constituted prophylactic removal of M3Ms with Sticky bone grafted in the study site as a primary predictor variable. Patients underwent 3 months of mandatory follow-up where pain, swelling, interincisal mouth opening, and gingival healing were measured on the 3 rd , 7 th , and 14 th day using the Numeric Rating Scale, anatomic landmarks, steel metric ruler, and criteria given by Landry et al . respectively. Radiological healing was calculated based on the height of the socket, Kelly's Index, and histogram values immediately after the procedure at 1 week, 1 month, and 3 months, respectively. Statistical comparison was made using Paired t -test. P < 0.05 was considered significant. Results: Forty-seven patients (mean 26.83 ± 6.58 years) demonstrated significantly lesser pain, swelling, and better gingival healing at the study site on multiple periods of follow-up. Rapid bone formation with superior density, lesser alveolar resorption, earlier bone blending, and trabecular formation were noticed on the study site with a significant difference at all time intervals. Discussion: Sticky bone was chosen as the graft owing to advantages such as simple preparation, convenient handling characteristics, safety, evident postoperative patient comfort, better retention of the clot, enhanced soft-tissue healing, absence of infection, and decreased osseous deformation as compared to the control site. This study validated the role of Sticky bone as an indispensable component of regenerative therapy in the orofacial osseous tissues as it was an ideal biologic graft with fibrin rich structure. Conclusion: This study validated the role of Sticky bone as an indispensable component of regenerative therapy in the orofacial osseous tissues as it was an ideal biologic graft with fibrin rich structure.

Effectiveness of Advanced Platelet-Rich Fibrin on Postoperative Sequelae for Impacted Mandibular Third Molar Surgery: A Prospective Study

“…However, our study results showed no significant difference in VAS scores on the 3rd and 7th postoperative days between the case and control groups. Similar results were found in another study which included 75 patients and they concluded that A-PRF has no positive effect on postoperative sequelae [ 21 ].…”

Clinical application of concentrate growth factors combined with bone substitute in Alveolar ridge preservation of anterior teeth

“…There are many different ARP techniques and various types of materials, such as autogenous bone [ 5 ], allografts [ 6 ], xenografts and platelet concentrates [ 7 , 8 ]. The main goal of the bone graft material is to serve as a scaffold and maintain a space for bone ingrowth, blood vessels formation, to support soft tissues and to improve the quality and quantity of regenerated bone [ 9 ]. DBBM is a classical xenogeneic bone graft material, which is made from deorganized bovine limb bone, and generally biocompatible and structurally similar to human bone.…”

Radiographic Evaluation of bone density after bone grafting associated with different laser bio-modulation techniques in rat

“…In 2020 Rupawala et al 16 investigated the bone regeneration capacity of sticky bone graft placed in extraction socket of lower wisdom tooth. In a split mouth study on 47 patients, the study compared the pain, swelling and stated a rapid bone healing with better bone density after 3 months.…”