2020
DOI: 10.1542/peds.2020-023861oo
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Efficacy of the Inquiring About Tolerance (EAT) Study Among Infants at High Risk of Developing Food Allergy

Abstract: The EAT study was a large randomized trial examining early introduction of common allergenic foods and risk of food allergy in children. This study examined the benefit of early food introduction in infants at high risk of developing food allergy.STUDY POPULATION: Participants were recruited from England and Wales. Secondary analysis was performed for 3 groups of high-risk infants: non-white (n 5 199), visible eczema (n 5 317), and infants with food sensitization defined as a serum IgE .0.01 kU/L (n 5 157).

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“…The authors record that the prevalence of food allergies, in general, was significantly decreased after the early exposure to allergens, while delayed contact resulted in a 7.3% prevalence, which is a considerable gap [21]. Nonetheless, early and late introduction of other allergens, namely cow's milk, sesame, fish, and wheat, appeared to have no distinction in the development of either sensitization or allergies [30,31]. Therefore, the authors propose that less potent allergens are less dependent on the timing of exposure.…”
Section: Studymentioning
confidence: 99%
“…The authors record that the prevalence of food allergies, in general, was significantly decreased after the early exposure to allergens, while delayed contact resulted in a 7.3% prevalence, which is a considerable gap [21]. Nonetheless, early and late introduction of other allergens, namely cow's milk, sesame, fish, and wheat, appeared to have no distinction in the development of either sensitization or allergies [30,31]. Therefore, the authors propose that less potent allergens are less dependent on the timing of exposure.…”
Section: Studymentioning
confidence: 99%