“…Out of the nine randomized clinical trials (10,11,12,13,14,15,16,17,18) reviewed for this systematic review, five studies (10,11,13,14,17) included asymptomatic teeth and another four studies (12,15,16,18) included symptomatic teeth. In the five studies (10,11,13,14,17) that assessed asymptomatic teeth, greater reduction of post operative pain was observed, thus presence of preoperative symptoms is considered an important confounding factor among the studies.…”