Efficiency of Tryptophan as a Niacin Precursor in the Young Chick

Baker, Dennis J.; Nk, Allen; Aj, Kleiss

doi:10.2527/jas1973.362299x

Cited by 27 publications

(3 citation statements)

References 10 publications

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“…The dietary requirement for tryptophan with excess niacin in the diet is 1300 mg/kg, for example, whereas the niacin requirement is only 20 mg/kg (Baker et al, 1973). In addition, vitamins generally have slower turnover rates than amino acids.…”

Section: Resultsmentioning

confidence: 99%

“…The basal crystalline amino acid diet shown in Table 1 was fed except it was supplemented with .2% choline'Cl, .35% DL-methionine, and .35% L-cystine. Niacin at 30 mg/kg is in slight excess of the chick's niacin requirement, whereas .13% dietary tryptophan precisely meets the chick's tryptophan requirement under conditions of niacin excess (Baker et al, 1973).…”

Section: Methodsmentioning

confidence: 99%

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Precursor (Amino Acid): Product (Vitamin) Interrelationship for Growing Chicks as Illustrated by Tryptophan-Niacin and Methionine-Choline

1983

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Experiments were conducted with crossbred chicks to examine the growth response to a vitamin when its precursor amino acid was in either deficient or adequate supply in the diet and vice versa. The tryptophan-niacin and methionine-choline interrelationships were thus examined. No growth responses to dietary niacin or choline were observed during severe tryptophan or methionine deficiency, respectively. However, when adequate levels of the precursor amino acids were present, marked gain and gain/feed responses to these vitamins occurred. In contrast, gain and feed efficiency responses to tryptophan or methionine occurred regardless of the chick's niacin or choline status, respectively.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Precursor (Amino Acid): Product (Vitamin) Interrelationship for Growing Chicks as Illustrated by Tryptophan-Niacin and Methionine-Choline

1983

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“…Crystalline forms of amino acids are supposed to be completely absorbed in the gut and fully available for anabolic purposes. Tryptophan (TRP) is utilized for body protein synthesis, but it is also a precursor of important non-protein substances, among others the neurotransmitter serotonin, which is involved in regulation of feed intake, resistance for stress and animal behaviour (Laycock and Ball, 1990;Rosebrough, 1996;Sève, 1999), and niacin, if diet is deficient in this vitamin (Baker et al, 1973).…”

Section: Introductionmentioning

confidence: 99%

Effects of acidifier added to diets containing graded levels of crystalline tryptophan on growth performance, protein digestibility, and on brain serotonin level in broiler chickens

Smulikowska¹,

Pastuszewska²,

Tomaszewska-Zaremba³

et al. 2004

J. Anim. Feed Sci.

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The objective of the study was to investigate whether addition of acidifier (A) to a diet containing crystalline tryptophan (TRP) does not impair utilization of the amino acid both for growth and serotonin synthesis in broiler chicken. Eight groups, each of 12 eight-day-old, individually housed, female broilers, were fed on diet containing 1.57 g TRP/kg, or diets supplemented with 0.21, 0.42 and 0.63 g TRP, without or with 3 g acidifier (A -mixture of phosphoric, citric and fumaric acids) per kg. Feed intake and body weight (BW) was registered for 3 weeks, followed by balance experiment, at the end the birds were killed and digesta and brain tissue were sampled.TRP supplementation increased BW gain and improved feed utilization (P<0.05), and did not affect ileal, while slightly decreased faecal protein digestibility. The concentration of serotonin (5-HT) and the ratio of 5-hydroxy-indole-3-acetic acid (5-HIAA) to 5-HT in brain tissue increased (P<0.01) with the increase of TRP level in diet. Supplementation with A had no significant effect on performance, pH of digesta, ileal and faecal protein digestibility in comparison with unsupplemented diets. However, it lowered the concentration of 5-HT (2.75 vs 2.98 μg/g; P<0.05) and increased the ratio of 5-HIAA/5-HT (0.30 vs 0.25; P<0.01) in brain tissue, the negative effect was greatest in TRP deficient diet (TRP × A; P<0.001). It indicate for a need of careful adjusting TRP level in broiler diets supplemented with acidifiers.

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Niacin

2000

Vitamins in Animal and Human Nutrition

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Efficiency of Tryptophan as a Niacin Precursor in the Young Chick

Cited by 27 publications

References 10 publications

Precursor (Amino Acid): Product (Vitamin) Interrelationship for Growing Chicks as Illustrated by Tryptophan-Niacin and Methionine-Choline

Precursor (Amino Acid): Product (Vitamin) Interrelationship for Growing Chicks as Illustrated by Tryptophan-Niacin and Methionine-Choline

Effects of acidifier added to diets containing graded levels of crystalline tryptophan on growth performance, protein digestibility, and on brain serotonin level in broiler chickens

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