Efficient Deuterium–Carbon REDOR NMR Spectroscopy

Measuring 13C–2D Dipolar Couplings with a Universal REDOR Dephasing Curve

“…Experimentally it is found that the REDOR experiment based on a simple pulse performs poorly (5,7,8). Sack et al have performed REDOR experiments by applying a train of deuterium composite pulses.…”

Peptide Torsion Angle Measurements: Effects of Nondilute Spin Pairs on Carbon-Observed, Deuterium-Dephased PM5-REDOR

“…Recently, we showed that PM5-REDOR pulses result in eigenvalues that increase the REDOR decay of powders containing 13 C-2 H spin pairs (12). A schematic representation of the eigenvalues of one of the spin pairs, together with the three transition frequencies that determine the REDOR oscillations of each crystallite in the powder, is presented in Fig.…”

“…This was done in a recent publication for a single carbondeuterium spin pair (12). There we transformed the dipolar part of the Hamiltonian to an interaction frame defined by the quadrupolar and RF Hamiltonians.…”

“…When the first term (H IS ) is diagonalized in the manifold of spin states of each spin pair separately, the 12 eigenstates with eigenvalues (energies) are of the form ͉␣ (12). The magnitudes of these eigenvalues are determined by the quadrupolar and dipolar I 1,2 S 1,2 tensor parameters in the rotating frame and depend on the shape and phases of the REDOR pulses on the S-deuterium spins.…”

“…Internuclear distance measurements between spin-1/2 and spin-1 deuterium ( 2 H) nuclei can be accurately measured using variations of standard spin-1/2 REDOR (6 -12). The method of PM5-REDOR (12) uses optimized phase-modulated pulses to obtain efficient 2 H dephasing.…”