PAD with the help of target domain data. However, it has always been a non-trivial challenge to collect sufficient data samples in the target domain, especially for attack samples. In the third work, we improve the cross-domain performance of the face PAD by only using a few genuine face samples collected in the target domain.We propose a method by introducing teacher-student learning to address the oneclass domain adaptation problem in face PAD. The similarity score between the representations of the teacher and student networks is used to distinguish attacks from genuine ones.To verify the effectiveness of the proposed methods, we devise protocols and conduct extensive experiments on multiple datasets. The experimental results show that our methods outperform prior methods.