The 15th International Workshop on Computational Transportation Science (IWCTS 2022) is particularly timely given the prominence of human mobility data, such as probe data from cell phones and connected automated vehicles, volunteered geographic information, and other sensing data. This unprecedented access to sensing data of mobility, and of integration of this analytics into smart cities management has led to innovations in intelligent transportation systems, building information management, and urban planning. Due to the scale of the data, these developments are deeply computational.