Efficient Synthesis of Dialkyl (2E)-2-(6H,12H-6,12-Epiminodibenzo[b,f][1,5] Dioxocin-13-yl)but-2-Enedioates via a Pseudo Four-Component Reaction

Abstract

An efficient pseudo four-component reaction between substituted 2-hydroxybenzaldehydes, ammonium acetate and different dialkyl but-2-ynedioates for the preparation of (2 E)-2-(6 H,12 H-6,12-epiminodibenzo[ b,f][1,5]dioxocin-13-yl)but-2-enedioates in moderate to good yields (60–83%) was developed. This method uses a variety of cheap and readily available reactants and a wide range of substrates. The structure of a typical product was confirmed by X-ray crystallography.