Eggerthia catenaformis bacteremia in a patient with an odontogenic abscess

Foronda, Carla; Calatrava, Elizabeth; Casanovas, Isabel; Martín-Hita, Lina; Navarro-Marí, José María; Cobo, Fernando

doi:10.1016/j.anaerobe.2019.04.007

Cited by 15 publications

(8 citation statements)

References 7 publications

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“…E. catenaformis , whose natural habitat is human feces, has only recently been associated with infections in humans. [ 4 5 ] In our case, the isolated E. catenaformis strain was multisensitive, but it had a moderately high MIC value for amoxicillin–clavulanate. The best MIC value was for clindamycin and benzylpenicillin.…”

Section: Discussionmentioning

confidence: 64%

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First case of deep neck and descending mediastinal abscess caused by dentoalveolar Eggerthia catenaformis infection

Cambi

Galassi

Meranda

et al. 2022

National Journal of Maxillofacial Surgery

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Descending mediastinal abscesses arising from oral (dental or peritonsillar abscess) or deep neck infections (DNIs) often become fatal without surgical drainage. Odontogenic origin was the most common cause of DNIs. We report the first clinical case of a patient with descending mediastinal abscess caused by DNI from Eggerthia catenaformis a Gram-positive anaerobic rod that can be rarely a human pathogen. The patient underwent the extraction of carious molars, cervical and thoracic surgical drainage, and targeted antibiotic therapy with resolution of the infection.

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Section: Discussionmentioning

confidence: 64%

“…[ 2 ] Recently, a second draft genome sequence of E. catenaformis has shown that this strain can be a human pathogen, and two patients with dental abscesses and one with a lung abscess and pleura empyema have been described. [ 3 4 5 ]…”

Section: Introductionmentioning

confidence: 99%

First case of deep neck and descending mediastinal abscess caused by dentoalveolar Eggerthia catenaformis infection

Cambi

Galassi

Meranda

et al. 2022

National Journal of Maxillofacial Surgery

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“…As a result, many of the reports stopped identification at the “ Lactobacillus spp.” level. Consequently, it is not possible to attribute with certainty those cases to lactobacilli also because a strictly related bacterium, Eggerthia catenaformis , considered to belong to the old genus Lactobacillus until 2011, is capable of causing infections [ 76 , 77 , 78 , 79 ] and can be confused with lactobacilli at the phenotypic level [ 80 ]. The studies that reported identification to the species level without reference to the identification method ( Table 1 ) probably used standardized colorimetric tests or MALDI-TOF mass spectrometry, largely applied in clinical laboratories [ 81 ].…”

Section: Discussionmentioning

confidence: 99%

Lactobacilli Infection Case Reports in the Last Three Years and Safety Implications

et al. 2022

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Lactobacilli constitute the dominant microbiota in many fermented foods and comprise widely used probiotics. However, these bacteria cause rare infections mostly in diabetic and immunocompromised subjects in presence of risk factors such as prosthetic hearth valves and dental procedures or caries. The scope of this survey was re-assessing the pathogenic potential of lactobacilli based on the infection case reports published in the last three years. In 2019, 2020, and 2021, total of 17, 15, and 16 cases, respectively, including endocarditis, bacteremia, and other infections, were reported. These annual numbers are higher than those observed previously. Lacticaseibacillus rhamnosus (13 cases), comprising strain GG (ATCC 53103) with established applications in healthcare, L. paracasei (7 cases), Lactobacillus acidophilus (5 cases), L. jensenii (5 cases), Lactiplantibacillus plantarum (3 cases), L. paraplantarum, L. delbrueckii subsp. delbrueckii, L. gasseri, L. paragasseri, Limosilactobacillus fermentum, and L. reuteri (1 case each) were involved. Virulence characterization of two strains that caused infections, a derivative of L. rhamnosus GG and L. paracasei LP10266, indicated that increased biofilm-forming capacity favors pathogenicity and it is determined by variable genetic traits. This survey highlights that the strains of lactobacilli that cause infections are little characterized genetically. Instead, to avoid that these bacteria become a hazard, genetic stability should be periodically re-evaluated by whole genome sequencing (WGS) to ensure that only non-pathogenic variants are administered to vulnerable individuals.

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“…level. Consequently, it is not possible to attribute with certainty those cases to lactobacilli also because a strictly related bacterium, Eggerthia catenaformis, considered to belong to the old genus Lactobacillus until 2011, is capable to cause infections [70,71,72,73] and can be confused with lactobacilli at the phenotypic level [74]. The studies that reported identification to the species level without reference to the identification method (Table 1) probably used standardized colorimetric tests or MALDI-TOF mass spectrometry, largely applied in clinical laboratories [75].…”

Section: Discussionmentioning

confidence: 99%

Lactobacilli Infection Case Reports in the Last Three Years and Safety Implications

Rossi¹,

Amadoro²,

Colavita³

2022

Preprint

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probiotics. However, these bacteria caused rare infections mostly in diabetic and immunocompromised subjects in presence of risk factors such as prosthetic hearth valves and dental procedures or caries. The scope of this survey was re-assessing the pathogenic potential of lactobacilli based on the infection case reports published in the last three years. In 2019, 2020 and 2021 17, 15 and 16 cases, respective-ly,.including endocarditis, bacteremia and other infections, were reported. These annual numbers are higher than observed previously. Lacticaseibacillus rhamnosus (13 cases), comprising strain GG (ATCC 53103) with established applications in healthcare, L. paracasei (7 cases), Lactobacillus acidophilus (5 cas-es), L. jensenii (5 cases), Lactiplantibacillus plantarum (3 cases), L. paraplantarum, L. delbrueckii subsp. del-brueckii, L. gasseri, L. paragasseri, Limosilactobacillus fermentum and L. reuteri (1 case each) were involved. Virulence characterization of two strains that caused infections, a derivative of L. rhamnosus GG and L.paracasei LP10266, indicated that increased biofilm forming capacity favors pathogenicity and it is determined by variable genetic traits. This survey highlighted that strains of lactobacilli able to cause infections were little characterized genet-ically. Instead, to avoid that these bacteria become a hazard, genetic stability should be periodically re-evaluated by whole genome sequencing (WGS) to ensure that only non-pathogenic variants are ad-ministered to vulnerable individuals.

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Eggerthia catenaformis bacteremia in a patient with an odontogenic abscess

Cited by 15 publications

References 7 publications

First case of deep neck and descending mediastinal abscess caused by dentoalveolar Eggerthia catenaformis infection

First case of deep neck and descending mediastinal abscess caused by dentoalveolar Eggerthia catenaformis infection

Lactobacilli Infection Case Reports in the Last Three Years and Safety Implications

Lactobacilli Infection Case Reports in the Last Three Years and Safety Implications

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