Eikenella corrodens Brain Abscess after Repeated Periodontal Manipulations Cured with Imipenem and Neurosurgery

Abstract

Eikenella corrodens is a facultatively anaerobic gram-negative rod that colonizes the oral cavity and very rarely produces central nervous system (CNS) infections. Frontal lobe abscesses are occasionally associated with a dental source of infection. We report a case of an adult man with overzealous dental cleaning habits who developed a right frontal brain abscess caused by E. corrodens. He underwent neurosurgical drainage of the pus and was successfully treated with imipenem 4 g/i.v./day for 4 weeks with no complications. Repeated periodontal trauma could explain the Eikenella brain abscess in this case.

A case of brain abscess due toEntamoebaspecies,Eikenella corrodensandPrevotellaspecies

“…Eikenella corrodens is also often associated with periodontal disease. 2 Prevotella sp. are Gram negative anaerobes, which belong to Bacteriodaceae, mostly associated with odontogenic infection.…”

Fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis

“…Only one patient had a monomicrobic F. necrophorum infection, whereas all others had polymicrobic infections involving F. nucleatum. 2,5 Experimental data have shown bacterial synergy between F. nucleatum and S. intermedius, 39 and between S. intermedius and Eikenella corrodens. (three patients), S. intermedius (two patients), and H. aphrophilus and Eikenella sp.…”

Profilaxis antimicrobiana previa a procedimientos dentales. Situación actual y nuevas perspectivas

“…Con la finalidad de evitar o reducir en lo posible algunas de estas situaciones se prescribe de manera preventiva antibiótico anticipado a procedimientos dentales, no sólo enfocado a la previsión de endocarditis infecciosa, sino también evitar en lo posible infecciones a distancia, ampliando así, el contexto de profilaxis antibiótica a profilaxis antimicrobiana. 3,4,[6][7][8][9][10][11] El uso de los antimicrobianos está indicado en pacientes odontológicos en diversas situaciones clínicas para evitar que, debido a los procedimientos realizados, se expongan a ciertos microorganismos patógenos que podrían constituir un riesgo importante de infección focal, causada por un foco de infección primario que se irradia a partes distales o sistémicas.…”