The determination of the optimum autofrettage pressure enables a clear improvement of the fatigue life for an internally highly pressurized component. The autofrettage process induces residual compressive stress after the release of a single static overload pressure, leading to plastic deformation at the inner wall whereas the outer part is only elastically stressed. This autofrettage pressure is clearly above the subsequent pulsating operating pressure range. Due to the complex geometry of the aluminium valve body, a detailed elastic–plastic finite element analysis is used to determine the critical area and the optimum autofrettage pressure. Based on an experimental stress–strain curve, three important load steps are simulated in a non‐linear way. The FKM guideline is used to assess fatigue life and crack initiation with detailed subsequent experimental verification. Even if small cracks occur, residual compressive stresses prohibit crack growth (nonpropagating crack), which can be analytically verified by fracture mechanical considerations (crack closure effect).