Ein seltener Nasopharynxtumor: M. Hodgkin

Strutz, Juergen; Zöllner, Ch.; Wannenmacher, M; Mann, W.

doi:10.1055/s-2007-998443

Cited by 3 publications

(2 citation statements)

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“…A review of 35 published cases of Hodgkin's disease involving the nasopharynx in which the histology was mentioned revealed a predominance of the mixed cellularity type (54%), followed by lymphocytic predominant (26%) and nodular sclerosis (20%) 6,9,11,12,15,16,20‐23 . Lymphocyte depleted nasopharyngeal Hodgkin's disease did not occur in any of these cases.…”

Section: Discussionmentioning

confidence: 93%

Isolated Nasopharyngeal Hodgkin's Disease Presenting as Nasal Obstruction

Malis

Moffat

McGarry

1998

Int J Clinical Practice

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SUMMARYLymphomas are the second most frequent malignancy affecting the head and neck. Within head and neck lymphomas, Hodgkin's disease accounts for only 10‐35% of all cases; 70‐80% of Hodgkin's disease of the head and neck involves nodal tissue, with extranodal Hodgkin's disease being most often found in the tissues of Waldeyer's ring. Extranodal Hodgkin's disease of the head and neck that does not involve Waldeyer's ring is extremely rare. We report a case of isolated extranodal Hodgkin's disease of the nasopharynx who presented to the rhinology clinic with symptoms of nasal obstruction. This unusual site, the possible reasons for its rarity and the investigations and management are discussed with reference to the literature.

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Section: Discussionmentioning

confidence: 93%

Isolated Nasopharyngeal Hodgkin's Disease Presenting as Nasal Obstruction

Malis

Moffat

McGarry

1998

Int J Clinical Practice

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“…Maligne Lymphome manifestieren sich außerhalb von Lymphknoten am häufigsten im Magen.Der Befall extranodaler Strukturen im Bereich des Waldeyer´schen Rachenringes ist im Kopf-Hals-Bereich der häufigste Manifestationsort, wobei der Nasopharynx häufiger betroffen ist als die Tonsillen oder der Zungengrund [3].Die isolierte, primäre Manifestation eines M.Hodgkin im Nasopharynx scheint hingegen ein selteneres Ereignis zu sein [6,8].Die häufigsten klinischen Beschwerden bei nasopharyngealer Lymphommanifestation sind, abgesehen von der Halslymphknotenschwellung, eine behinderte Nasenatmung und Rhinorrhoe, seltener Ohrbeschwerden, die durch eine Tubenfunktionsstörung bedingt sind [1].…”

Section: Befall Des Nasopharynxunclassified

Ausgeprägte Halslymphknotenschwellung bei nasopharyngealem Tumor

Folz¹,

Lippert²,

Werner³

2000

HNO

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Hodgkin Lymphoma of the Nasopharynx: Case Report with Review of the Literature

Owosho

Gooden

McBee³

2015

Head and Neck Pathol

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We report an uncommon case and histopathologic work-up of Hodgkin lymphoma of the nasopharynx in a 49-year old female patient who presented with a 2-year complaint of bilateral nasal congestion. Histologic study revealed a lymphocyte rich subtype of classic Hodgkin lymphoma. Immunohistochemical analysis revealed CD15, CD30, OCT-2, BOB.1, and MUM-1 expression by the neoplastic cells and a lack of expression of CD45, CD20, CD3, EMA, and EBER. The review of the literature showed that Hodgkin lymphoma of the nasopharynx is rare, the most common reported subtype is the mixed cellularity, and Hodgkin lymphoma of the nasopharynx has a favorable prognosis.

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Ein seltener Nasopharynxtumor: M. Hodgkin

Cited by 3 publications

References 1 publication

Isolated Nasopharyngeal Hodgkin's Disease Presenting as Nasal Obstruction

Isolated Nasopharyngeal Hodgkin's Disease Presenting as Nasal Obstruction

Ausgeprägte Halslymphknotenschwellung bei nasopharyngealem Tumor

Hodgkin Lymphoma of the Nasopharynx: Case Report with Review of the Literature

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