The lateral vibrations of slender footbridges caused by walking pedestrians have been the subject of many studies over the last few decades. However, despite the large amount of research, a common design guidance has not been set yet. The phenomenon of experiencing excessive lateral accelerations (generally known as the lock-in effect) occurs in low-damped structures with natural frequencies in the range 0.4-1.3 Hz when the number of pedestrians on the footbridge is above a certain "critical number". The lock-in behaviour is characterised by a sudden increase in the amplitude of vibrations, usually associated with resonant loads but that can also be explained by the phenomenon of interaction between pedestrians and the structure. Pedestrians are biomechanical systems that generate ground reaction forces while walking, due to the acceleration or deceleration of their centre of mass. The lateral force is the consequence of the action of keeping the body balance during walking and can be affected by the ground stability. As people perceive the floor vibration, they modify their gait in order to avoid losing balance. People interact with the structure, generating the auto-induced force in the natural frequency of the footbridge, with independence of the pedestrian frequency. This phenomenon, known as human-structure interaction (HSI), is widely accepted as the main cause of the sudden onset of high amplitudes of vibration. However, the current design recommendations do not include an expression for the auto-induced component of the pedestrian action and, as a consequence, it is not possible to evaluate the footbridge comfort once the lock-in effect has developed.